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Gestodene Micro Powder | Progestin

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  • Specifications

Buy Manufacturer Progestin Micro Powder Gestodene online

 

What is Gestodene?

Gestodene is a progestin which is used in combination with the estrogen ethinylestradiol as a hormonal contraceptive.

 

Gestodene Chemical Profile

CAS: 60282-87-3
MF: C21H26O2
MW: 310.43
EINECS: 262-145-8
Chemical Properties White Crystalline Solid
Purity: 99.5%
Usage Orally active gestogen with progesterone-like profile of activity. Used in combination with estrogen as oral contraceptive

 

Gestodene Certificate Of Analysis

Test Items Specification Test Results
Description White or almost white crystalline powder White crystalline powder
Melting Point 191.0~193.0ºC 192ºC
Loss of drying ≤1.0% 0.5%
Heavy Metal ≤20ppm 15ppm
TLC Only one spot Only one spot
Assay ≥99.5% 99.91%
Conclusion It complies with the USP 32.

 

Gestodene Application

The main use for gestodene is as an oral contraceptive. It mimics the naturally occurring female sex hormone progesterone, which is partially responsible for regulating the menstrual cycle. In order to be effective as a contraceptive,a synthetic version of the other female sex hormone,estrogen, is combined with gestodene.

 

Gestodene Effects:

Gestodene is androgenically neutral, meaning that contraceptive pills containing gestodene do not exhibit the androgenic side effects (e.g. acne, hirsutism, weight gain) often associated with second-generation contraceptive pills, such as those containing levonorgestrel.

The synthetic estrogen dosage in third-generation contraceptive pills (including those containing gestodene) is lower than that in second-generation oral contraceptives, reducing the likelihood of weight gain, breast tenderness and migraine. Third-generation oral contraceptives are also suitable for use in patients with diabetes or lipid disorders because they have minimal impact on blood glucose levels and the lipid profile.

 

Gestodene Side effects

Women who take oral contraceptives containing gestodene are 5.6 times as likely to develop venous thromboembolism than women who do not take any contraceptive pill, and 1.6 times as likely to develop venous thromboembolism compared to women taking oral contraceptives containing levonorgestrel.

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