Buy USP35 Corticosteroid Raw Powder Hydrocortisone 17-butyrate Online
What is Hydrocortisone 17-butyrate?
Hydrocortisone 17-butyrate is a form of hydrocortisone butyrate.
Hydrocortisone butyrate topical is used to help relieve redness, itching, swelling, or other discomfort caused by skin conditions (e.g., atopic dermatitis, seborrheic dermatitis). This medicine is a corticosteroid (cortisone-like medicine or steroid).
Hydrocortisone 17-butyrate Basic information
Prodcut name: Hydrocortisone butyrate
Synonym: hydrocortisone 17-butyrate;(11beta)-11,21-dihydroxy-3,20-dioxopregn-4-en-17-yl butanoate; (9xi,11beta,14xi)-11,21-dihydroxy-3,20-dioxopregn-4-en-17-yl butanoate
CAS Registry Number: 13609-67-1
Assay: 97.0%~102.0%
Packaging: 1kg/foil bag
Molecular Formula: C25H36O6
Molecular Weight: 432.5497
Appearance: White or almost white crystalline powder
Hydrocortisone 17-butyrate Certificate Of Analysis
Product Name |
Hydrocortisone 17-butyrate |
CAS No. |
13609-67-1 |
Outer Packing |
1kg/bag |
Production date |
11th Jan 2018 |
Shelf life |
10th Jan 2021 |
Standard adopted |
USP35 |
Item |
Specification |
Result |
Appearance |
White to cream, crystalline powder |
White
crystalline
powder |
Identification (by IR) |
Conforms to the CRS spectrum |
Conforms |
Melting Point |
Approximately 196 °C |
196°C |
Specific rotation |
+98°~+104°(dried substance) |
+99.7° |
Loss on drying |
≤2.0% |
0.2% |
Residue on ignition |
≤0.1% |
0.06% |
Heavy metals |
≤20ppm |
Conforms |
Related substance (by HPLC) |
Any impurity ≤1.0% |
0.22% |
Total impurities ≤2.0% |
0.31% |
Assay(by HPLC) |
Contains 97.0% to 102% of C25H32CIFO5
calculated on
dried basis |
99.9% |
Residual solvents |
Ethanol ≤3000ppm |
262ppm |
Aceton ≤500ppm |
Undetected
(LOD 4ppm) |
Pyriding ≤100ppm |
Undetected
(LOD 3ppm) |
N,N-Dimethylformamide ≤100ppm |
Undetected
(LOD 10ppm) |
Conclusion |
Meet the specification according to USP35 |
Hydrocortisone 17-butyrate Usage
Use this medication on the skin only. However, do not use it on the face, groin, or underarms unless directed to do so by your doctor.
Wash and dry your hands before using. Clean and dry the affected area. Apply a thin film of medication to the affected area and gently rub in. Apply the ointment, cream, or solution form of this medication usually 2-3 times daily or as directed by your doctor. Apply the lotion form of this medication usually 2 times daily or as directed. Do not bandage, cover, or wrap the area unless directed to do so by your doctor. If used in the diaper area on an infant, do not use tight-fitting diapers or plastic pants.
After applying the medication, wash your hands unless you are using this medication to treat the hands. When applying this medication near the eyes, avoid getting it in theeyes because this may worsen or cause glaucoma. Also, avoid getting this medication in the nose or mouth. If you get the medication in these areas, rinse with plenty of water.