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USP35 Hydrocortisone 17-butyrate Powder | Corticosteroid Raw Material

» Hormone Powder » Glucocorticoids » USP35 Hydrocortisone 17-butyrate Powder | Corticosteroid Raw Material

  • Specifications

Buy USP35 Corticosteroid Raw Powder Hydrocortisone 17-butyrate Online

 

What is Hydrocortisone 17-butyrate?

Hydrocortisone 17-butyrate is a form of hydrocortisone butyrate.

Hydrocortisone butyrate topical is used to help relieve redness, itching, swelling, or other discomfort caused by skin conditions (e.g., atopic dermatitis, seborrheic dermatitis). This medicine is a corticosteroid (cortisone-like medicine or steroid).

 

Hydrocortisone 17-butyrate Basic information

Prodcut name: Hydrocortisone butyrate
Synonym: hydrocortisone 17-butyrate;(11beta)-11,21-dihydroxy-3,20-dioxopregn-4-en-17-yl butanoate; (9xi,11beta,14xi)-11,21-dihydroxy-3,20-dioxopregn-4-en-17-yl butanoate
CAS Registry Number: 13609-67-1
Assay: 97.0%~102.0%
Packaging: 1kg/foil bag
Molecular Formula: C25H36O6
Molecular Weight: 432.5497
Appearance: White or almost white crystalline powder

 

Hydrocortisone 17-butyrate Certificate Of Analysis

Product Name Hydrocortisone 17-butyrate
CAS No. 13609-67-1 Outer Packing 1kg/bag
Production date 11th Jan 2018 Shelf life 10th Jan 2021
Standard adopted USP35
Item Specification Result
Appearance White to cream, crystalline powder White 
crystalline 
powder
Identification (by IR) Conforms to the CRS spectrum Conforms
Melting Point Approximately 196 °C 196°C
Specific rotation +98°~+104°(dried substance) +99.7°
Loss on drying ≤2.0% 0.2%
Residue on ignition ≤0.1% 0.06%
Heavy metals ≤20ppm Conforms
Related substance (by HPLC) Any impurity ≤1.0% 0.22%
Total impurities ≤2.0% 0.31%
Assay(by HPLC) Contains 97.0% to 102% of C25H32CIFO5 
calculated on 
dried basis
99.9%
Residual solvents Ethanol ≤3000ppm 262ppm
Aceton ≤500ppm Undetected
(LOD 4ppm)
Pyriding ≤100ppm Undetected
(LOD 3ppm)
N,N-Dimethylformamide ≤100ppm Undetected
(LOD 10ppm)
Conclusion Meet the specification according to USP35

 

Hydrocortisone 17-butyrate Usage

Use this medication on the skin only. However, do not use it on the face, groin, or underarms unless directed to do so by your doctor.

Wash and dry your hands before using. Clean and dry the affected area. Apply a thin film of medication to the affected area and gently rub in. Apply the ointment, cream, or solution form of this medication usually 2-3 times daily or as directed by your doctor. Apply the lotion form of this medication usually 2 times daily or as directed. Do not bandage, cover, or wrap the area unless directed to do so by your doctor. If used in the diaper area on an infant, do not use tight-fitting diapers or plastic pants.

After applying the medication, wash your hands unless you are using this medication to treat the hands. When applying this medication near the eyes, avoid getting it in theeyes because this may worsen or cause glaucoma. Also, avoid getting this medication in the nose or mouth. If you get the medication in these areas, rinse with plenty of water.

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