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Prednisolone Powder | Corticosteroid Raw Drug

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Factory Supply Corticosteroid Raw Drug Prednisolone Powder Online

 

What is Prednisolone?

Prednisolone is a steroid medication used to treat certain types of allergies, inflammatory conditions, autoimmune disorders, and cancers. Some of these conditions include adrenocortical insufficiency, high blood calcium, rheumatoid arthritis, dermatitis, eye inflammation, asthma, and multiple sclerosis. It is used by mouth, injection into a vein, as a skin cream, and as eye drops

 

Prednisolone Basic Information

CAS: 50-24-8 
EINECS: 200-021-7 
Quality Standards: BP 
Assay: 97.0%~102.0% 
Molecular formula: C21H28O5 
Molecular weight: 360.44 
Appearance: Almost white crystalline powder
Loss on drying:  ≤ 1.00%          
Density: 1.28g/cm3 
Melt point: 240º C 
Boiling point: 579.8º C at 760 mmHg 
Flash point: 198.4º C 
Vapour pressure: 7.36E-16mmHg at 25º C 
Usage: Applicable to rheumatoid arthritis, rheumatic fever, such as lupus erythematosus, dermatomyositis, multiple myeloma, but also making hydrogenated prednisone acetate. 
Storage: This product should be kept sealed in a cool and dry place. 

 

Prednisolone Certificate of Analysis

Product name Prednisolone
CAS No. 50-24-8 Outer Packing 1kg
Production date 11th Jan 2018 Shelf life 10th Jan 2021
Standard adopted EP7/BP2011
Items of analysis Specification Results
Appearance White or almost white crystalline powder Almost white crystalline powder
Identification A: IR;B: TLC   Positive
Specific Rotation  +96°-+102° +98°
Loss On Drying ≤ 1.00%        0.66%
Any impurity Between≤0.5and≤1.0%    1%
Total impurity ≤ 2.0% 0.74%
Total impurities ≤2.0%  1.5 %
Assay   97.0%-103.0%    99.4%
Methanol ≤3000ppm  757ppm
Dichloromehtane ≤600ppm 28ppm
Conclusion Qualified

 

Prednisolone Medical uses

  • Prednisolone is useful for the treatment of a wide range of inflammatory and autoimmune conditions such as asthma, uveitis, pyoderma gangrenosum, rheumatoid arthritis, ulcerative colitis, pericarditis, temporal arteritis and Crohn’s disease, Bell’s palsy, multiple sclerosis, cluster headaches, vasculitis, acute lymphoblastic leukemia and autoimmune hepatitis, systemic lupus erythematosus, Kawasaki disease, dermatomyositis, and sarcoidosis.
  • Prednisolone can also be used for allergic reactions ranging from seasonal allergies to drug allergic reactions.
  • Prednisolone can also be used as an immunosuppressive drug for organ transplants.
  • Prednisolone in lower doses can be used in cases of primary adrenal insufficiency (Addison’s disease).
  • Corticosteroids inhibit the inflammatory response to a variety of inciting agents and, it is presumed, delay or slow healing. They inhibit the edema, fibrin deposition, capillary dilation, leukocyte migration, capillary proliferation, fibroblast proliferation, deposition of collagen, and scar formation with inflammation.

 

Prednisolone Side Effects

Serious side effects may include mental health problems and an increased risk of infection.

Common side effects with long-term use include osteoporosis, cataracts, weakness, easy bruising, and yeast infections. Short-term use around the time of delivery is safe for the baby; however, long-term use during pregnancy may result in harm. Methylprednisolone is in the glucocorticoid family of medication.

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