» Solutions / Conversion Recipes » L-Epinephrine Hydrochloride Powder | Sympathomimetic Hormone
L-Epinephrine hydrochloride is the active sympathomimetic hormone from the ADRENAL MEDULLA. It stimulates both the alpha- and beta- adrenergic systems, causes systemic VASOCONSTRICTION and gastrointestinal relaxation, stimulates the HEART, and dilates BRONCHI and cerebral vessels. It is used in ASTHMA and CARDIAC FAILURE and to delay absorption of local ANESTHETICS.
Product name | L-Epinephrine Hydrochloride, Adrenalin hydrochloride |
Purity | 100.5% |
CAS Registry Number | 55-31-2 |
Einecs No | 200-230-3 |
MF | C9H14ClNO3 |
MW | 219.67 |
Appearance | White crystal powder |
Storage | Shading, confined preservation |
Usage | Antishock, Asthma treatment |
Product name | L-Epinephrine hydrochloride | ||
CAS No. | 329-63-5 | Outer Packing | 1kg/bag |
Production date | 12th.01.2018 | Shelf life | 11th.01.2021 |
Standard adopted | USP35 | ||
Items of analysis | Specification | Results | |
Appearance | White or almost-white crystalline powder | PASS | |
Identification | A:Ultraviolet Absorption B:meets the tests for Chloride | PASS | |
Water(BK KF) | ≤0.5% | 0.2% | |
Specific rotation | between -1° and +1° | 0° | |
Residue on ignition | ≤0.5% | PASS | |
Limit of adrenalone | at 310 nm not more than 0.2 | 0.002 | |
Limit of norepinephrine bitartrate | ≤4.0% | 0 | |
Residuai vents | Methanol 3000PPM | 2962PPM | |
Assay(Dried base) | 97.0%—102.0% | 100.2% | |
Packing and storage | Preserve in tight, light-resistant containers | Preserve in tight, light-resistant containers | |
Conclusion | Qualified |
1. Epinephrine Hydrochloride is the hydrochloride salt of the naturally occurring sympathomimetic amine with vasoconstricting, intraocular pressure-reducing, and bronchodilating activities.
2. By stimulating vascular alpha-adrenergic receptors, epinephrine causes vasoconstriction, thereby increasing vascular resistance and blood pressure. When administered in the conjunctiva, this agent binds to alpha-adrenergic receptors in the iris sphincter muscle, resulting in vasoconstriction, a decrease in the production of aqueous humor, and a lowering of intraocular pressure.
3. Through its beta1 receptor-stimulating actions, epinephrine increases the force and rate of myocardial contraction and relaxes bronchial smooth muscle, resulting in bronchodilation.