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Isoprenaline Sulphate Powder | Bradycardia Treatment
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What is Isoprenaline sulphate?
Isoprenaline, or isoproterenol, is a medication used for the treatment of bradycardia (slow heart rate), heart block, and rarely for asthma. In humans, it is a non-selective β adrenoreceptor agonist that is the isopropylamine analog of epinephrine (adrenaline)
Isoprenaline sulphate Basic Information
Other name: 4-[1-Hydroxy-2-[(1-methylethyl)amino]ethyl]-1,2-benzenediol sulfate (2:1)
CAS NO.:299-95-6299-95-6
MW: 520.59
MF: 2(C11H17NO3).H2SO4
EINECS NO.: 206-085-2
Appearance: white or almost white crystalline powder
Assay: 99.0%min
Isoprenaline sulphate Specification:
| Appearance | White or almost white, crystalline powder |
| Solubility | Freely soluble in water, very slightly soluble in water |
| Melting Point | About 128 ℃,with decomposition |
| Identification | A: Corresponds to reference standard
B: Test of sulphates: positive C: Dilute 1ml of solution S to 10ml with water R D: Solution S gives reaction (a) of sulphates |
| Appearance of
solution |
Clear and not more intensely coloured than reference solution Y6 |
| PH | 4.3 to 5.5 |
| Isoprenalone | The absorbance not more than 0.2 |
| Water | 5.0% to 7.5% |
| Sulphated ash | Maximum 0.1%, determined on 1.0g |
| Assay | 99.6%, 98.0% to 102.0% (anhydrous substance) |
Isoprenaline sulphate Usage
Isoprenaline sulphate is used to treat heart block and episodes of Adams-Stokes syndrome that are not caused by ventricular tachycardia or fibrillation, in emergencies for cardiac arrest until electric shock can be administered, for bronchospasm occurring during anesthesia, and as an adjunct in the treatment of hypovolemic shock, septic shock, low cardiac output (hypoperfusion) states, congestive heart failure, and cardiogenic shock