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Dutasteride (Duagen, Avodart) Powder | Anti-Hair Loss Drug

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  • Specifications

Factory Supply 99.8% Purity Anti-Hair Loss Dutasteride (Duagen, Avodart) Powder

 

What is Dutasteride?

Dutasteride, sold under the brand name Avodart among others, is a medication used primarily to treat enlarged prostate in men. It can also be used to treat scalp hair loss in men, excessive hair growth in women, and as a part of hormone therapy for transgender women. It is taken by mouth.

Dutasteride is a 5α-reductase inhibitor and works by decreasing the production of dihydrotestosterone (DHT), an androgen sex hormone, in certain parts of the body like the prostate gland and the scalp. It inhibits all three forms of 5α-reductase and can decrease DHT levels in the blood by up to 98%

 

Dutasteride Basic Information

Product name Dutasteride
Alias Duagen; Avodart
CAS 164656-23-9
Assay 99%
Molecular formula C27H30F6N2O2
Molecular weight 528.53
Melting point 242°C~250°C
Appearance White to pale yellow powder
Storage Shading, confined preservation.  

 

Dutasteride certificate of analysis

Product name Dutasteride
CAS No. 164656-23-9 Outer Packing 1KG/drum
Production date 19th Jan 2018 Shelf life 18th Jan 2020
Standard adopted Enterprise Standard.
Items of analysis Specification Results
Description White or off- white powder Off- white powder
Identification (IR) Should match with working standard complies
Solubility soluble in dichloromethane, slightly soluble in ethyl acetate, methanol, insoluble in water complies
Melting point 246.0~252.0℃ 248.0℃~249.0℃
Water by KF Not more than 0.5% 0.14%
Loss on drying Not more than 0.5% 0.15%
Residue on ignition Not more than 0.2% 0.08%
Heavy Metals Not more than 20ppm complies
Single maximum impurity Not more than 0.5% 0.10%
Total impurities Not more than 1.0% 0.22%
Assay by HPLC 98.0% —102.0% 99.8%
Conclusion Qualified

 

Dutasteride Medical uses

Prostate enlargement: Dutasteride is used for treating benign prostatic hyperplasia (BPH)
Scalp hair loss
Excessive hair growth
Prostate cancer
Transgender women: Dutasteride is sometimes used as a component of hormone therapy for transgender women in combination with an estrogen and/or another antiandrogen like spironolactone. It may be useful for treating scalp hair loss or in those who cannot tolerate spironolactone

 

Dutasteride Dosage

Dutasteride, at 2.5mgs/day is roughly 1.5X more effective than Finasteride at 5mgs/day, at treating hair loss (both halting it as well as regrowing it). In addition, Avodart can be used successfully at that same dose to treat prostate enlargement, and a lesser known effect of Avodart (again, at that same dose) use is to treat Acne caused by an overabundance of androgens in the body. 

 

Dutasteride Side effects

Side effects are generally mild. The FDA has warned that the drug increases the risk of certain rare forms of prostate cancer, and that some men may experience sexual dysfunction, depression, anxiety, or breast enlargement.

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