Buy Progesterone Powder Online Raw endogenous steroid and progestogen sex hormone CAS: 57-83-0
What is Progesterone?
Progesterone is an endogenous steroid and progestogen sex hormone involved in the menstrual cycle, pregnancy, and embryogenesis of humans and other species. It belongs to a group of steroid hormones called the progestogens,[12] and is the major progestogen in the body. Progesterone has a variety of important functions in the body. It is also a crucial metabolic intermediate in the production of other endogenous steroids, including the sex hormones and the corticosteroids, and plays an important role in brain function as a neurosteroid.
In addition to its role as a natural hormone, progesterone is used as a medication, for instance in menopausal hormone therapy.
Progesterone Basic information
Synonyms: PROGESTERONE-WATER SOLUBLE;progestin;PROGESTERONE;PRIMOLUT;17alpha-Hydroxy-6alpha-methylpregn-4-ene-3,20-dione;17alpha-Progesterone;3,20-Pregnene-4;4-Pregnen-3,20-dion
CAS: 57-83-0
MF: C21H30O2
MW: 314.46
EINECS: 200-350-6
Progesterone Certificate of Analysis
| Product name |
Progesterone |
| CAS No. |
57-83-0 |
Outer Packing |
1kg/bag |
| Production date |
2018.2.5 |
Shelf life |
2021.2.4 |
| Standard adopted |
EP7 |
| Items of analysis |
Specification |
Results |
| appearance |
White or almost white crystalline power or colorless crystals |
white crystalline power, micronized |
| assay |
97.0-103.0% |
99.5% |
| infrared absorption |
the transmission minima in the IR spectrum obained with the substance correspond in position and relative size to those in the spectrum obtained with progessterone CRS. |
complies |
| thin-layer chromatography |
conforms to results A and results B |
complies |
| specific rotation |
+186° to 194° |
+188° |
| impurity B |
0.5% max |
0.09% |
| impurity C |
0.5% max |
0.2% |
| impurity G |
0.5% max |
not detected |
| any unspecified impurity |
0.1% max |
0.03% |
| total impurities |
0.8% max |
0.3% |
| loss on drying |
0.5% max |
0.1% |
| granularity |
D(0.90)≤20μm |
11.852um |
| Conclusion |
Qualified |
Progesterone Application
Women take progesterone by mouth for inducing menstrual periods; and treating abnormal uterine bleeding associated with hormonal imbalance, and severe symptoms of premenstrual syndrome (PMS). Progesterone is also used in combination with the hormone estrogen to “oppose estrogen” as part of hormone replacement therapy. If estrogen is given without progesterone, estrogen increases the risk of uterine cancer.
Progesterone is also used to ease withdrawal symptoms when certain drugs (benzodiazepines) are discontinued.
Progesterone cream is sometimes used in hormone replacement therapy and for treating menopausal symptoms such as hot flashes. Topical progesterone is also used for treating or preventing certain allergies in which hormones play a role; and for treating bloating, breast tenderness, decreased sex drive, depression, fatigue, lumpy (fibrocystic) breasts, headaches, low blood sugar, increased blood clotting, infertility, irritability, memory loss, miscarriages, brittle bones (osteoporosis), bone loss in younger women, symptoms of PMS, thyroid problems, “foggy thinking,” uterine cancer, uterine fibroids, water retention, weight gain, and vaginal irritation (vulval lichen sclerosis).
Progesterone gel is sometimes used inside the vagina to expand the cervix (cervical ripening), treat breast pain in women with noncancerous breast disease, and to prevent and treat abnormal thickening of the lining of the uterus (endometrial hyperplasia).
Progesterone is also used intravaginally or by injection for treating infertility and symptoms of (PMS).
