Buy NSI-189 Powder Online Raw Antidepressant For Major Depressive Disorder Treatment CAS 1270138-40-3
What is NSI-189?
NSI-189 is an experimental, potential antidepressant that is under investigation by Neuralstem, Inc. for the treatment for major depressive disorder (MDD), as well as for cognitive impairment and neurodegeneration.
A phase II clinical trial for MDD failed to meet the primary depression endpoint (MADRS) in July 2017, although statistically significant improvements have been reported on a number of secondary depression and cognition endpoints
NSI-189 Certificate of Analysis
Product name: NSI-189
Chemical name:2-[(3-Methylbutyl)amino]-3-pyridinyl][4-(phenylmethyl)-1-piperazinyl]methanone
CAS:1270138-40-3
Molecular Structure C22H30N4O
Molecular Weight 366.50
Appearance: off-white powder
Purity: 99%
Usage: nootropic
Package: 100g per bag
NSI-189 Certificate of Analysis
| Product name |
NSI-189 |
| CAS No. |
1270138-40-3 |
Outer Packing |
|
| Production date |
Feb. 7th. 2018 |
Shelf life |
Feb. 6th. 2021 |
| Standard adopted |
in-house standard |
| Items of analysis |
Specification |
Results |
| Appearance |
Off-white powder |
Confrom |
| Identification |
IR and HPLC spectrum shall conform to the standard sample |
conform |
| Melting Point |
83℃～86℃ |
84.3℃～85.6℃ |
| Loss on Drying |
Less than 0.5% |
0.29% |
| Purity(On Dried Base,HPLC) |
NLT 99.5 % |
99.62% |
| Total Impurity |
Less than 0.5% |
0.33% |
| Residue On Ignition |
≤0.2% |
0.16% |
| Heavy metal |
≤20ppm |
conform |
| Conclusion |
Qualified |
NSI-189 Uses
In addition to MDD, Neuralstem has said that it intends to pursue clinical development of NSI-189 for a variety of other neurological conditions, including traumatic brain injury, Alzheimer’s disease, post-traumatic stress disorder, stroke, and to prevent cognitive and memory decline in aging.
How Does NSI-189 works ?
This drug was developed to address three important aspects of depression including hippocampal volume, neurogenesis and neurotransmission. NSI-189 increases the volume within the hippocampus. In so doing, hippocampal volume and healthy brain cell density is increased thereby improving mod and cognitive performance. Aside from increasing hippocampal volume, the drug also improves neuronal cell functionality. It works it promoting healthy neuronal cell growth whilst repair damaged areas in the brain.
NSI-189 Dosage and Suggestion:
Studies conducted to evaluate effects of NSI-189 revealed that 40 to 80 mg daily is effective in treating depression and cognitive symptoms amongst healthy patients. In these trials, there are no serious adverse events recorded. Generally, NSI-189 is well tolerated and safe for human use.
