Buy Citalopram hydrobromide (Citalopram HBr) Powder Online Raw Antidepressants For Depression mental disorders Treatment CAS 59729-32-7
Citalopram Hydrobromide Basic introduction:
Product Name: Citalopram hydrobromide
Chemical Name:1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydroisobenzofuran-5-carbonitrile monohydrobromide
CAS:59729-32-7
MF:C20H22BrFN2O
MW:405.3
EINECS:261-890-6
Assay:99%min
Appearence:White Crystalline Powder
Drug Category:Antidepressant drug
Purpose:An inhibitor of serotonin (5-HT) uptake. Used as an antidepressant
Package:25kg/drum
Citalopram Hydrobromide Description:
Citalopram hydrobromide (citalopram HBr) is an orally administered selective serotonin reuptake inhibitor (SSRI) with a chemical structure unrelated to that of other SSRIs or of tricyclic, tetracyclic, or other available antidepressant agents.
Citalopram HBr occurs as a fine, white to off-white powder. Citalopram HBr is sparingly soluble in water and soluble in ethanol.
The tablet is available as the brand-name drug Celexa. In Australia, the UK, Germany, Portugal, Poland, and most European countries, it is licensed for depressive episodes and panic disorder with or without agoraphobia. In Spain, it is also used for obsessive-compulsive disorder.
The advantage of this drug is that it has no effect on cholinergic muscarinic receptors, histamine receptors and α-adrenergic receptors . Because if these receptors are inhibited, a lot of side effects caused by antidepressants will produce, such as dry mouth, sedation, orthostatic hypotension. Citalopram hydrobromide is effective for not only endogenous depression patients but also non-endogenous depression patients. Its antidepressant effect is usually established after 2-4 weeks . Citalopram hydrobromide does not affect the cardiac conduction system and blood pressure, which is particularly important for elderly patients. In addition, citalopram hydrobromide does not affect the blood, liver and kidney systems. Rare side effects and the most mild sedative properties make it particularly suitable for long-term treatment.It does not lead to weight gaining,and it does not strengthen the role of alcohol.
Citalopram Hydrobromide COA
| Contents |
Specification |
Results |
| Appearance |
White crystailine or powder |
conform |
| Identification |
a) Infrared absorption
b) High performance liquid chromatography
c) Meets the requirements of the best for bromide |
conform |
| Solubility |
Freely soluble in water, in alcohol, and chloroform |
conform |
| Specific rotation |
Between -0.2°and +0.2° at 20° |
conform |
| Completeness of solution |
The absorbance at 410nm of a 2.5% w/v solution,
in 96% alcohol, against a sample solvent in a l-cm quartz cell is not more than 0.040 |
conform |
| Organic volatile impurities |
Chloroform: not more than 60 ug/g
1,4-Dioxane:not more than 380ug/g
Methylenc Chloride not more than 600 ug/g
Irichloroethylenc: not more than 80 ug/g |
conform |
| PH |
Between 5.5 to 6.5 |
6.0 |
| Heavy metals |
Not more than 0.002% |
conform |
| Residue on ignition |
Not more than 0.1% |
0.06% |
| water |
Not more than 0.5% |
0.2% |
| Assay(on dried basis) |
Not more than 98.0 and than 102.0% |
99.2% |
| Conelusion: Conforming to USP36 |
