Metformin Hydrochloride Powder Hypoglycemic Agents For Type 2 Diabetes
Metformin hydrochloride Specification
Product Name: Metformin Hydrochloride
CAS:1115-70-4
Standard: USP35
Natural/Synthetic: Synthetic
Level: Pharmaceutical grade
Content: 99%
Appearance: white crystal
Packing: 25/cardboard drum
Ingredients: metformin hydrochloride
Physicochemical properties: This product is a white crystalline powder; odorless. This product is soluble in water, dissolved in methanol, slightly soluble in ethanol, insoluble in chloroform or ether.
Category: Pharmaceutical Raw Materials
Industry: Pharmaceuticals
Field: Hypoglycemic
Deferred Products: Hypoglycemic Agents
Use: For non-insulin-dependent diabetes mellitus; reduce fasting and postprandial hyperglycemia in type 2 diabetes
Usage and dosage: Oral: Start increasing dose from low dose. Usually the starting dose is 0.5g once, twice a day; or 0.85g, once a day; taken with meals; can be increased by 0.5g per week, or increased by 0.85g every 2 weeks, and gradually increased to 2g per day. Take it again.
What is Metformin hydrochloride?
Metformin hydrochloride is indicated as an adjunct to diet and exercise to improve glycemic control in adults and children with type 2 diabetes mellitus
Metformin Hydrochloride Certificate Of Analysis
| Product name |
Metformin Hydrochloride |
| CAS No. |
1115-70-4 |
Outer Packing |
25kg/drum |
| Production date |
20180226 |
Shelf life |
2021.2.25 |
| Standard adopted |
USP35 |
| Items of analysis |
Specification |
Results |
| Appearance |
white crystalline，odorless |
complies |
| Assay |
98.5—101.0% |
99.90% |
| Cyanoguanidine |
NMT 0.02% |
0.01% |
| any other single impurity |
NMT 0.1% |
＜0.1% |
| Loss On Drying |
≤0.5% |
0.09% |
| Heavy Metals |
≤10PPm |
＜10PPm |
| Residue On Ignition |
≤0.1% |
0.05% |
| Conclusion |
Qualified |
Metformin Hydrochloride Side Effects
The most common adverse effect of metformin is gastrointestinal irritation, including diarrhea, cramps, nausea, vomiting, and increased flatulence; metformin is more commonly associated with gastrointestinal side effects than most other antidiabetic medications.
The most serious potential side effect of metformin use is lactic acidosis; this complication is very rare, and the vast majority of these cases seem to be related to comorbid conditions, such as impaired liver or kidney function, rather than to the metformin itself.
