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Griseofulvin Powder Raw Antifungal Medication For Dermatophytoses

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Buy Griseofulvin Powder Raw Antifungal Medication For Dermatophytoses Online CAS 126-07-8

 

Griseofulvin Specification

Product Name: Griseofulvin
CAS: 126-07-8
Content: 99%
Appearance: light yellow powder
Packing: 20KG / cardboard drums
Components: 1’S,6’R)-6′-Methyl-2′,4,6-trimethoxy-7-chloro-spiro[benzofuran-2(3H),1′-[2]cyclohexene ]-3,4′-Dione; Photometric HPLC
Physical and chemical properties: white or almost white powder; odorless, slightly bitter taste. Solubility: This product is easily soluble in dimethylformamide, slightly soluble in absolute ethanol and very slightly soluble in water.
Category: Pharmaceutical Raw Materials
Field: Antifungal antibiotics
Deferred products: medical antifungal antibiotics
Use: For head lice, severe tinea corporis, stacked corrugated pedicures, hand-foot pedicures, etc., the efficacy of tinea capitis is more obvious. Some cases may recur, but retreatment can still work. The nail file often takes several months to take effect, so it is appropriate to use other drugs. Has a certain therapeutic effect on herpes zoster.
Usage and dosage: oral administration: Adult (1) hyperthyroidism and athlete’s foot, 500mg once, once every 12 hours; (2) tinea capitis, tinea corporis or tinea cruris, once 250mg, once every 12 hours, or once 500mg , once a day. Pediatrics (1) People 2 to 14 years of age weighing 14 to 23 kg, once 62.5 to 125 mg, once every 12 hours, or 125 to 250 mg once daily. (2) pediatric body weight greater than 23kg, once 125 ~ 250mg, once every 12 hours, or 250 ~ 500mg, once daily. 0.1g tablets/0.25g tablets, 0.125g capsules

 

What is Griseofulvin?

Griseofulvin is an antifungal medication used to treat a number of types of dermatophytoses (ringworm). This includes fungal infections of the nails and skin when antifungal creams have not worked.

 

Griseofulvin Certificate of Analysis

Product name Griseofulvin
CAS No. 126-07-8 Outer Packing 20KG/drum
Production date 2017.08.27 Shelf life 2021.08.26
Standard adopted BP2013/EP8
Items of analysis Specification Results
Characteristics A white or yellowish-white, microfine powder Yellowish-white microfine powder
Melting point About 220℃ 220.5℃
Specific optical rotation +354°~+364° +357.8°
Identification Meets the requirements Meets the requirements
Check-up Particles size Meets the requirements Meets the requirements
Acidity 0.25g consumed 0.02mol/L NaOH not more than 1.0ml 0.6ml
Clarity and colour of solution The solution is clear and not more intensely coloured than reference solution Y4 clear Y5-Y6
Matter soluble in petroleum spirit ≤0.2% 0.10%
Sulphated ash ≤0.2% 0.08%
Related substances -CL:<0.60 -H:<0.15 -CL:0.24 -H:0.08
Loss on drying ≤1.0% 0.08%
Abnormal toxicity Meets the requirements Meets the requirements
Assay(on the anhydrous substance) 97.0%~102.0% 99.2%
Conclusion Qualified

 

Griseofulvin Side Effects

Common side effects include allergic reactions, nausea, diarrhea, headache, trouble sleeping, and feeling tired. It is not recommended in people with liver failure or porphyria. Use during or in the months before pregnancy may result in harm to the baby.

Griseofulvin works by interfering with fungal mitosis.

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