Buy Miconazole Nitrate Powder Raw APIS Azole Antifungal Online CAS 22832-87-7
Miconazole Nitrate Specification
Product Name: Miconazole nitrate
CAS: 22832-87-7
Standard: USP
Content: 99%
Appearance: white powder
Number of meshes:60
Packing: 25KG/cardboard drum
Ingredients: 1-[2-(2,4-Dichlorophenyl)-2-[(2,4-dichlorophenyl)methoxy]ethyl]-1H-imidazolium nitrate C18H14Cl4N2O·HNO3
Physicochemical properties: white or almost white crystalline or crystalline powder; odorless or almost odorless. This product is slightly soluble in methanol, slightly soluble in chloroform or ethanol, insoluble in water or ether.
Category: Pharmaceutical Raw Materials
Field: Antifungal drugs
Deferred product: Miconazole nitrate 20 mg tincture
Use: For body tinea, jock itch, hand, athlete’s foot, tinea versicolor, paronychia, and candidal vulvovaginitis; can also be used for bacterial skin infections and otitis externa
Usage and dosage: external use, spray on the affected area, sooner or later. Contains 20 mg of miconazole nitrate per ml. Excipients: dimethyl sulfoxide, flavor, ethanol.
Miconazole Nitrate Certificate of Analysis
| Product name |
Miconazole nitrate |
| CAS No. |
22832-87-7 |
Outer Packing |
25KG drum |
| Production date |
2018.03.26 |
Shelf life |
2021.03.25 |
| Standard adopted |
USP36 |
| Items of analysis |
Specification |
Results |
| Characteristics |
White or white crystalline powder |
Complies |
| Identification |
Infrared absorption and standard |
Complies |
| Solution clarity |
Solution is clear, color is not deep in the standard Y7 |
Complies |
| Solubility |
Difficult to dissolve in water, soluble in ethanol, slightly soluble in ethanol |
Complies |
| Optical rotation |
-0.1°-+0.1° |
0° |
| Impurity A |
≤0.25% |
0.14% |
| Impurity B |
≤0.25% |
0.02% |
| Impurity C |
≤0.25% |
0.03% |
| Impurity D |
≤0.25% |
0.03% |
| Impurity E |
≤0.25% |
0.02% |
| Impurity F |
≤0.25% |
N/A |
| Impurity G |
≤0.25% |
N/A |
| Individual unspecified impurity |
≤0.10% |
0.02% |
| Total impurity |
≤0.5% |
0.26% |
| Melting Point |
178-184℃ |
180.5-181.1℃ |
| Loss On Drying |
≤0.5% |
0.15% |
| Residue on ignition |
≤0.1% |
0.05% |
| Toluene |
≤890ppm |
110ppm |
| Ethanol |
≤5000ppm |
120ppm |
| Benzyl chloride |
≤1000ppm |
100ppm |
| 2,4-Dichlorobenzyl chloride |
≤1000ppm |
ND |
| Assay（On Dry Basis |
98.5-101% |
99.4% |
| Conclusion |
Qualified |
Miconazole Nitrate Application
Miconazole Nitrate is used to treat vaginal yeast infections. Miconazole reduces vaginal burning, itching, and discharge that may occur with this condition. This medication is an azole antifungal. It works by stopping the growth of yeast (fungus) that causes the infection. The vaginal product comes in 2 forms (a vaginal cream or tablet). Some products also come with a skin cream to be applied to the area around the outside of the vagina.
