Buy Cyclosporin A (Ciclosporin) Powder Raw APIS Immunosuppressant Medication Online CAS 59865-13-3
Cyclosporin A Specification
Product Name: Cyclosporine A
CAS: 59865-13-3
Standard: USP
Level: Pharmaceutical grade
Content: 99%
Appearance: white powder
Packing: 1KG/Aluminum
Physical and chemical properties: white or almost white powder; odorless. This product is very soluble in methanol, ethanol or acetonitrile, soluble in ethyl acetate, dissolved in acetone or ether, almost insoluble in water.
Category: Pharmaceutical Raw Materials
Field: Immunosuppressants
Down products: cyclosporine oral solution, cyclosporine soft capsules, pills, oral solution
Use: Mainly used for liver, kidney and heart transplantation anti-rejection reaction, can be used with adrenocorticotropic hormone, can also be used for the treatment of some immune diseases.
What is Cyclosporin A (Ciclosporin) ?
Ciclosporin, also spelled cyclosporine and cyclosporin, is an immunosuppressant medication and natural product. It is taken by mouth or by injection into a vein for rheumatoid arthritis, psoriasis, Crohn’s disease, nephrotic syndrome, and in organ transplants to prevent rejection.
It is also used as eye drops for keratoconjunctivitis sicca (dry eyes).
Cyclosporin A Certificate of Analysis
| Product name |
CYCLOSPORINE |
| CAS No. |
79217-60-0;59865-13-3 |
Outer Packing |
1KG/foil bag |
| Production date |
2017.11.09 |
Shelf life |
2021.11.08 |
| Standard adopted |
USP36 |
| Items of analysis |
Specification |
Results |
| Appearance |
White crystalline powder |
White crystalline powder |
| Solubility |
To comply |
Complies |
| Identification |
To comply |
Complies |
| Loss on drying |
2.0% max |
0.4% |
| Heavy metals |
0.002% max |
＜0.002% |
| individual impurity |
0.7% max |
0.39% |
| sum of all impurity |
1.5% max |
1.43% |
| Any other impurity |
0.1% max |
0.07% |
| Acetone |
0.5% max |
0.29% |
| Ethanol |
0.5% max |
0.01% |
| Ethyl acetate |
0.5% max |
0.02% |
| ASSAY |
98.5%～101.5% |
98.7% |
| Conclusion |
Qualified |
Cyclosporin A (Ciclosporin) Side Effects
Common side effects include high blood pressure, headache, kidney problems, increased hair growth, and vomiting. Other severe side effects include an increased risk of infection, liver problems, and an increased risk of lymphoma. Blood levels of the medication should be checked to decrease the risk of side effects. Use during pregnancy may result in preterm birth; however, ciclosporin does not appear to cause birth defects.
