USP36 China Local Anesthetic Drugs Prilocaine Hydrochloride Prilocaine HCl Citanest 99.46% Pure Powder
What is Prilocaine hydrochloride?
Prilocaine hydrochloride is a local anesthetic of the amino amide type first prepared by Claes Tegner and Nils Lö Fgren. In its injectable form, it is often used in dentistry. It is also often combined with lidocaine as a preparation for dermal anesthesia (lidocaine/prilocaine or EMLA), for treatment of conditions like paresthesia. As it has low cardiac toxicity, it is commonly used forintravenous regional anaesthesia.
In some patients, a metabolite of prilocaine may cause the unusual side effect of methemoglobinemia, which may be treated with methylene blue.
Local anesthetic is a substance that causes loss of sensation only to the area to which it is applied without affecting consciousness. Most local anesthetics structures have amino-ester or an amino-amide group which are linked to hydrophilic (secondary or tertiary amine) and to hydrophobic group (aromatics) on the other side.
Local anesthetics, long duration, lower toxicity, chemicals that are also small Suitable for epidural anesthesia, block anesthesia and infiltration anesthesia, etc
Prilocaine hydrochloride Basic Info
Synonym: Citanesthydrochloride, l-67hydrochloride, Prilocainechloride, Xylonest, Propitocaine HCl, Prilocaine
CAS: 1786-81-8
MF: C13H21ClN2O
MW: 256.77
EINECS: 217-244-0
Assay: 99.5%
Quality Standards: USP36/Pharma Grade
Appearance: White powder
Catalog: Antibacterial
Package: 25kg/Drum
Origin: China
Type: Intermediates
Quality: Refined
Packing: foil bag
Transport Package:Secret Packaging
Prilocaine hydrochloride Certificate Of Analysis
| Product name |
Prilocaine hydrochloride |
| CAS No. |
1786-81-8 |
Outer Packing |
25kg/drum |
| Production date |
2018.01.02 |
Shelf life |
2020.01.01 |
| Standard adopted |
USP36 |
| Items of analysis |
Specification |
Results |
| Solubility |
Freely soluble in water and in alcohol ，slightly soluble in chloroform，very slightly soluble in acetone; practically insoluble in ether |
Complies |
| Identification |
By IR absorption,To match with working standard |
Complies |
| Should be positive response |
Complies |
| Should display the reaction of chloride differentiated |
Complies |
| Complies |
Complies |
166～168℃ |
| Loss on drying |
≤ 0.3% |
0.13% |
| Residue on ignition |
≤0.1% |
0.03% |
| Heavy metals |
≤0.002% |
＜0.002% |
| Residual solvents |
Should be to match with the standard |
Complies |
| Complies |
99.0% ～101.0%（on the anhydrous basis) |
99.46% |
| Conclusion |
Qualified |
