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Azathioprine (Imuran) Powder Raw Immunosuppressive Medication

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Buy Azathioprine Powder Azathioprine (Imuran) Raw Immunosuppressive Medication Online CAS 446-86-6

 

Azathioprine Specification

Product Name: Azathioprine
CAS: 446-86-6
Level: Pharmaceutical Grade
Content: 99%
Appearance: light yellow powder
Packing: 5KG/inner bag detachable
Ingredients: 6-[5-(1-Methyl-4-nitro-1H-imidazolyl)thio]-1H-purine. Calculated on dry products, with C9H7N7O2S not less than 98.0%
Physicochemical properties: light yellow powder or crystalline powder; odorless, slightly bitter taste. This product is very slightly soluble in ethanol, almost insoluble in water; easily soluble in ammonia solution
Category: Pharmaceutical Raw Materials
Industry: Pharmaceuticals
Field: Immunosuppressive drugs
Deferred products: Azathioprine tablets
Application: It is mainly used for inhibiting immune rejection in allogeneic transplantation. It is often used together with corticosteroids or anti-lymphocyte globulin (ALG). Also widely used in rheumatoid arthritis, systemic lupus erythematosus, autoimmune hemolytic anemia, idiopathic thrombocytopenic purpura, active chronic hepatitis, ulcerative colitis, myasthenia gravis, scleroderma and other autoimmunities Sexual disease. For chronic nephritis and nephrotic syndrome, its efficacy is inferior to that of cyclophosphamide. Because its adverse reactions are still many and serious, the treatment of the above diseases is not the preferred drug, usually only when corticosteroids alone cannot be controlled.
Dosage: Oral daily 1.5mg ~ 4mg/kg, once or divided dose on the 1st; allogeneic transplantation, daily 2mg ~ 5mg/kg, once or divided dose on the day; leukemia, daily 1.5mg ~ 3mg /kg, orally or on a daily basis.

 

What is Azathioprine?

Azathioprine (Imuran), is an immunosuppressive medication. It is used in rheumatoid arthritis, granulomatosis with polyangiitis, Crohn’s disease, ulcerative colitis, and in kidney transplants to prevent rejection. It is taken by mouth or injected into a vein.

 

Azathioprine  Certificate of Analysis

Product name Azathioprine
CAS No. 446-86-6 Outer Packing 5kg/bag
Production date 2017.09.24 Shelf life 2020.09.23
Standard adopted USP35
Items of analysis Specification Results
Appearance Pale yellow powder Conforms
Identification A: IR B: TLC Conforms
Acidity or Alkalinity NMT 0.1ml of HCL 0.020N or NMT 0.1 ml of NaOH 0.020N Conforms
Loss on Drying 1.0 %Max 0.35%
Residue On Ignition 0.1 %Max 0.06 %
Mercaptopurine (TLC) 1.0 %Max Conforms
Assay(dry basis) 98.0-101.5% 99.8%
Conclusion Qualified

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