Buy Aztreonam (Azactam) Powder Antibiotic Pharmaceutical Raw Materials Online CAS 78110-38-0
Aztreonam Specification
Product Name: Aztreonam
CAS: 78110-38-0
Level: Medical grade
Content: 98%
Appearance: white powder
Packing: 5KG packaging / 25KG cardboard drum detachable
Category: Pharmaceutical raw materials
Field: Pharmaceutical raw materials
Downcast product: Aztreonam
Application: It has the characteristics of weak immunogenicity and less cross-allergic to penicillins and cephalosporins. Therefore, it can be used as an alternative to aminoglycosides to treat aerobic Gram-negative bacteria infection in patients with renal dysfunction; For patients who are allergic to penicillin and cephalosporins.
Dosage: Aztreonam can be administered by intravenous drip, intravenous or intramuscular injection. Aztreonam 1. Adult patients with normal renal function: 1 urinary tract infection, once 0.5g or 1g, once every 8 hours or 12 hours. 2 moderate infection, 1 time 1g or 2g, once every 8 hours or 12 hours. 3 severe infection, 1 time 2g, hourly or 8 hours; the maximum daily dose is 8g. 4 Pseudomonas aeruginosa infection should be administered at a severe infection dose. 2. Children: once 30mg/kg, once every 8 hours; severe infection can be increased to every 6 hours, the maximum daily dose is 120mg/kg.
What is Aztreonam?
Aztreonam is an antibiotic used primarily to treat infections caused by gram-negative bacteria such as Pseudomonas aeruginosa. This may include bone infections, endometritis, intra abdominal infections, pneumonia, urinary tract infections, and sepsis. It is given by injection into a vein or muscle or breathed in as a mist.
Aztreonam Certificate of Analysis
| Product name |
Aztreonam |
| CAS No. |
78110-38-0 |
Outer Packing |
25kg/drum |
| Production date |
20150308 |
Shelf life |
20170307 |
| Standard adopted |
USP32 |
| Items of analysis |
Specification |
Results |
| Characters |
White or yellowish crystalline powder |
Conform |
| Specific rotation |
-26°~-32° |
-28° |
| Identification |
|
|
| IR |
The infrared absorption spectrum is consis tent with the spectrum of aztreonam refreence Substance |
Conform |
| HPLC |
The retention times of the major peaks is con sistent with the standard preparation as obta ined in the Assay |
Conform |
| PH |
2.2~2.8 |
2.4 |
| Water |
Not more than 2.0% |
0.2% |
| Related Substance |
|
|
| Desulfonated Aztreonam |
Not more than 1.0% |
0.67% |
| Aztreonam E-Isomer |
Not more than 1.0% |
0.24% |
| Any individual impurity |
Not more than 1.5% |
0.33% |
| Total impurity |
Not more than 3.0% |
1.75 |
| Residual solvents |
|
|
| Ethanol |
Not more than 2.0% |
1.7% |
| Residua on ignition |
Residua on ignition |
Conform |
| Heavy Metals |
Not more than 10ppm |
Conform |
| Bacterial endotoxins |
Less than 0.17EU/mg |
Conform |
| Sterility |
Should meet the requirement |
Conform |
| Assay |
It contains not less than 94 percent and not more than 102 percent of Azt Reonam(C13H17N5O8S2) |
95.6% |
| Conclusion |
Qualified |
