Buy Female Hormone Estrogen Estriol Powder CAS 50-27-1
What is Estriol?
Estriol (also oestriol or E3) is one of the three main estrogens produced by the human body. Estriol is only produced in significant amounts during pregnancy as it is made by the placenta from 16-hydroxydehydroepiandrosterone sulfate (16-OH DHEAS),an androgen steroid made in the fetal liver and adrenal glands.
Levels of estriol in non-pregnant women do not change much after menopause, and levels are not significantly different from levels in men.
Estriol Chemical Profile
CAS: 50-27-1
MF: C18H24O3
MW: 288.38
EINECS: 200-022-2
Melting point: 281.5ºC
Properties: white crystalline powder, odorless
Type: Natural hormone, Estrogen and progestin drugs
Estriol Certificate Of Analysis
ITEM |
SPECIFICATION |
RESULT |
Character |
White or almost white crystalline powder |
White crystalline powder |
Specific rotation |
+54°to +62° |
+59.9° |
Completeness of solution |
Clear and free from undissolved solid |
Conforms |
Identification |
(1) complies by IR (2) complies by UV |
Conforms Conforms |
Residue on Ignition |
Not more than 0.1% |
0.05% |
Loss on drying |
Not more than 0.5 |
0.1% |
Chromatographic purity |
Total impurities not more than 2.0% |
<2.0% |
Assay |
It should contain 97.0% to 102.0% of C18H24O3 calculated on dried basis |
98.4% |
Particle size |
It should be 90% below 30μm |
Conforms |
Conclusion |
Conforms to USP36 |
Estriol Application
Estriol is used for the treatment of menopausal symptoms . Double-blind, placebo-controlled studies and other controlled trials have found oral or vaginal estriol effective for symptoms of menopause, including hot flashes, night sweats, insomnia, vaginal dryness, and recurrent urinary tract infections. Estriol may also help prevent.