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Levonorgestrel Powder

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  • Specifications

Buy Levonorgestrel Powder Online Raw Birth Control Hormonal Medication Progesterone drug Supplier Manufacturer CAS 797-63-7

 

What is Levonorgestrel?

Levonorgestrel is a hormonal medication which is used in a number of birth control methods

Levonorgestrel is used by women to prevent pregnancy after birth control failure (such as a broken condom) or unprotected sex. This medication is an emergency contraceptive and should not be used as a regular form of birth control. It is a progestin hormone that works mainly by preventing the release of an egg (ovulation) during your menstrual cycle. It also makes vaginal fluid thicker to help prevent sperm from reaching an egg (fertilization) and changes the lining of the uterus (womb) to prevent attachment of a fertilized egg.

 

Levonorgestrel Basic information

English Synonyms: 13-ethyl-17-alpha-ethynyl-17-beta-hydroxy-4-gonen-3-one;13-ethyl-17-alpha-ethynylgon-4-en-17-beta-ol-3-one;13-ethyl-17-hydroxy-19-dinor-17-alpha-pregn-4-en-20-yn-3-on(+)-1;17-alpha-ethinyl-13-beta-ethyl-17-beta-hydroxy-4-estren-3-one;17-beta-hydroxy-18-methyl-19-nor-17-alpha-pregn-4-en-20-yn-3-one;17-ethynyl-18-methyl-19-nortestosteron;17-ethynyl-18-methyl-19-nortestosterone;18-methyl-17-alpha-ethynyl-19-nortestosterone
Cas NO.: 797-63-7
EINECS: 212-349-8
Assay: 99%
Molecular Formula:C21H28O2
Molecular Weight:312.45
Quality Standard: USP40
Packing:1kg/foil bag/tin
Appearance: White or almost white crystalline powder
Usage: Progesterone drug, used for irregular menstruation, functional uterine bleeding, endometriosis, etc

Levonorgestrel Certificate of Analysis

Product name Levonorgestrel
CAS No. 797-63-7 Outer Packing 1KG
Production date 2018.01.13 Shelf life 2023.01.12
Standard adopted USP40
Items of analysis Specification Results
Description White or practically white crystalline powder, odorless White crystalline powder 
Specific Rotation -30°~-35° -33°
Identification IR (197k) Conforms
Loss on Drying ≤0.5% 0.12%
Residue on Ignition ≤0.3% 0.06%
Limit of Ethynyl Group 7.81%~8.18% 7.88%
Single Impurity ≤ 0.5% <0.5%
Total Impurities ≤ 2.0% ≤ 2.0%
Ethanol ≤5000ppm 445ppm
Assay 98.0% to 102.0% 99.5%
Melting Range 232~239℃ 233~237℃
Particle size 90%≤10um Conforms
Conclusion Qualified

 

Levonorgestrel Medical uses

1. Birth control pills: At low doses, levonorgestrel is used in monophasic and triphasic formulations of combined oral contraceptive pills, with available monophasic doses ranging from 100–250 µg, and triphasic doses of 50 µg/75 µg/125 µg. It is combined with the estrogen ethinylestradiol in these formulations.

At very low daily dose of 30 µg, levonorgestrel is used in some progestogen only pill formulations.

2. Emergency birth control: Levonorgestrel is used in emergency contraceptive pills (ECPs), both in a combined Yuzpe regimen which includes estrogen, and as a levonorgestrel-only method. The levonorgestrel-only method uses levonorgestrel 1.5 mg (as a single dose or as two 0.75 mg doses 12 hours apart) taken within 3 days of unprotected sex, with one study indicating that beginning as late as 120 hours (5 days) after intercourse could be effective.

 

Levonorgestrel Side effects

After intake of 1.5 mg levonorgestrel in clinical trials, very common side effects (reported by 10% or more) included: hives, dizziness, headache, nausea, abdominal pain, uterine pain, delayed menstruation, heavy menstruation, uterine bleeding, and fatigue; common side effects (reported by 1% to 10%) included diarrhea, vomiting, and painful menstruation; these side effects usually disappeared within 48 hours.

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