Buy Pregnenolone (P5) Powder Online Raw Endogenous Steroid Neurosteroid Manufacturer CAS 145-13-1
What is Pregnenolone?
Pregnenolone (P5), or pregn-5-en-3β-ol-20-one, is an endogenous steroid and precursor/metabolic intermediate in the biosynthesis of most of the steroid hormones, including the progestogens, androgens, estrogens, glucocorticoids, and mineralocorticoids. In addition, pregnenolone is biologically active in its own right, acting as a neurosteroid.
Pregnenolone Basic information
Product Name: Pregnenolone
CAS: 145-13-1
MF: C21H32O2
MW: 316.48
EINECS: 205-647-4
MP: 188-190 ° C
Alpha: 28.5 º (c=1, EtOH)
Storage temp.: Refrigerator
Merck: 7733
Chemical Properties: White to off-white powder
Usage: Pregnenolone is a steroid hormone involved in the steroidogenesis of progesterone, mineralocorticoids, glucocorticoids, androgens, and estrogens. As such it is a prohormone. Pregnenolone is a GABAA antagonist and increases neurogenesis in the hippocampus.
Pregnenolone Certificate of Analysis
| Product name |
Pregnenolone |
| CAS No. |
145-13-1 |
Outer Packing |
1kg per bag |
| Production date |
2018.02.10 |
Shelf life |
2022.02.09 |
| Standard adopted |
Company standard |
| Items of analysis |
Specification |
Results |
| Characteristics |
Whtie powder |
Conform |
| Solubility |
Almost insoluble in water，soluble in dichloromethane |
Conform |
| Identification |
TLC and HPLC |
Conform |
| Appearance |
clear |
clear |
| Melting point |
184~193℃ |
185.6~192.3℃ |
| Specific rotation |
+27.5~+31.5°（C=EtOH） |
+29.2° |
| Related sunstances |
Single impurity ≤0.50%
Total impurities ≤1.0% |
0.25%
0.42% |
| Loss on drying |
≤0.50% |
0.27% |
| Purity |
≥99% |
99.58% |
| Conclusion |
Qualified |
Pregnenolone Application
Pregnenolone is used for fatigue and increasing energy; Alzheimer’s disease and enhancing memory; trauma and injuries; as well as stress and improving immunity.
It is also is used for skin disorders including psoriasis and scleroderma.
Women use pregnenolone for lumpy breasts (fibrocystic breast disease), a disorder of the lining of the uterus (endometriosis), symptoms of menopause, and premenstrual syndrome (PMS).
Some people use pregnenolone for slowing or reversing aging, arthritis, and depression. It is also used for strengthening the heart, allergic reactions, “detoxification,” lupus, multiple sclerosis (MS), prostate problems, and seizures.
