Buy Tianeptine Sodium Powder Online Raw Antidepressant For Major Depressive Disorder Treatment CAS 30123-17-2
What is Tianeptine?
Tianeptine is an atypical antidepressant which is used mainly in the treatment of major depressive disorder, although it may also be used to treat anxiety, asthma, and irritable bowel syndrome. In terms of chemical structure, it is technically a tricyclic antidepressant (TCA), but it has a very different drug profile than other TCAs, and is not usually grouped with them.
Tianeptine sodium Certificate Of Analysis
| Product name |
Tianeptine sodium |
| CAS No. |
30123-17-2 |
Outer Packing |
1KG |
| Production date |
2018.02.08 |
Shelf life |
2020.02.07 |
| Standard adopted |
EP9.0 |
| Items of analysis |
Specification |
Results |
| Description |
White to yellowish powder,very hygroscopic |
Off-white powder,very hygroscopic |
| Solubility |
Freetly soluble In water and methanol and dichloromethane |
Complies |
| Identification |
（1）By IR, To match with working standard;（2）It gives reaction of sodium |
Complies |
| Impurities A |
≤0.1% |
Not detected |
| Any impurity |
≤0.1% |
0.03% |
| Total impurities |
≤0.4% |
0.10% |
| Acetidin |
≤ 0.5% |
Not detected |
| Dichloromethane |
≤ 0.06% |
Not detected |
| Methanol |
≤ 0.3% |
Not detected |
| Acetone |
≤ 0.5% |
Not detected |
| Acetonitrile |
≤0.041% |
Not detected |
| Ethanol |
≤0.5% |
Not detected |
| N, N-dimethylformamide |
≤0.088% |
Not detected |
| Water |
≤ 5.0% |
1.09% |
| Assay |
99.0%-101.0% |
100.61% |
| Conclusion |
Qualified |
Tianeptine Medical uses on Depression and anxiety
Tianeptine shows efficacy against serious depressive episodes (major depression), comparable to amitriptyline, imipramine and fluoxetine, but with significantly fewer side effects.
Tianeptine was shown to be more effective than maprotiline in a group of people with co-existing depression and anxiety.
Tianeptine also displays significant anxiolytic properties and is useful in treating a spectrum of anxiety disorders including panic disorder, as evidenced by a study in which those administered 35% CO2 gas (carbogen) on paroxetine or tianeptine therapy showed equivalent panic-blocking effects. Like many antidepressants (including bupropion, the selective serotonin reuptake inhibitors, the serotonin-norepinephrine reuptake inhibitors, moclobemide and numerous others) it may also have a beneficial effect on cognition in people with depression-induced cognitive dysfunction.
Tianeptine Other Uses
Tianeptine has been found to be effective in depression, in Parkinson’s disease, and in post-traumatic stress disorder of which it was as safe and effective as fluoxetine and moclobemide
Tianeptine has been reported to be very effective for asthma.
Tianeptine Side effects
Compared to other TCAs it produces significantly fewer cardiovascular, anticholinergic (like dry mouth or constipation), sedative and appetite-stimulating effects.
A recent review found that it was amongst the antidepressants most prone to causing hepatotoxicity (liver damage), although the evidence to support this concern was of limited quality.
Although not well studied with tianeptine, it has been shown for tricyclic antidepressants that they may cause cardiac arrhythmias.
