Buy Raw Anticholinergic Bronchodilator APIs Tiotropium bromide (Spiriva) Powder Online
What is Tiotropium bromide?
Tiotropium bromide, originally marketed as Spiriva,[1] is a long-acting, 24-hour, anticholinergic bronchodilator used in the management of chronic obstructive pulmonary disease (COPD)
Tiotropium bromide Basic Information
Product Name |
Tiotropium bromide |
CAS |
136310-93-5 |
MF |
C19H22BrNO4S2 |
MW |
472.42 |
Apperance |
White Solid |
Usage |
Muscarinic receptor antagonist. Bronchodilator |
Tiotropium bromide certifIcate Of Analysis
Product name |
Tiotropium bromide |
CAS No. |
136310-93-5 |
Outer Packing |
1kg/bag |
Production date |
13th Jan 2018 |
Shelf life |
12th Jan 2020 |
Standard adopted |
Enterprise Standard |
Items of analysis |
Specification |
Results |
Appearance |
White or yellowish white powder or crystal |
Conforms |
Solubility |
Slightly soluble in water, soluble in methanol, insoluble in dichloromethane |
Conforms |
Identification |
(1) IR infrared spectrum; (2) Typical reaction of bromide |
Conforms |
Residue on ignition |
≤0.1% |
0.06% |
Water |
≤0.5% |
0.36% |
Impurity C |
≤0.3% |
Conforms |
Impurity F |
≤0.15% |
Conforms |
Impurities A,E |
≤0.15% |
Conforms |
Impurities G,H |
≤0.1% |
Conforms |
Unknown Impurities |
≤0.1% |
Conforms |
Total Impurities |
≤0.3% |
0.29% |
Isomer |
≤0.1% |
0.09% |
Assay |
≥99.0% |
99.71% |
Graininess |
D100:≤20 µm |
Conforms |
Conclusion |
Qualified |
Tiotropium bromide Medical Uses
Tiotropium is used for maintenance treatment of chronic obstructive pulmonary disease (COPD) which includes chronic bronchitis and emphysema.[3] It is not however used for acute exacerbations
Tiotropium bromide side effects
dry mouth and/or throat irritation. Rarely (<0.1% of patients) treatment is associated with:urinary retention, constipation, acute angle closure glaucoma, palpitations (notably supraventricular tachycardia and atrial fibrillation) and/or allergy (rash, angioedema, anaphylaxis).