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Cefotaxime Sodium Powder Raw Antibiotic Drug

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Buy Cefotaxime Sodium Powder Raw Antibiotic Powder For Bacterial Infections CAS 64485-93-4

 

Cefotaxime sodium Specification

Product Name: Cefotaxime Sodium
CAS: 64485-93-4
Appearance: white powder
Packaging: 5KG/Aluminum
Ingredients: (6R,7R)-3-[(Acetoxy)methyl]-7-[(2-amino-4-thiazolyl)-(methoxyimino)acetylamino)-8-oxo-5 -Thia-1-azabicyclo[4.2.0]oct-2-ene-2-methyl formate
Physicochemical properties: white to light yellow crystals or powder; odorless or slightly special odor. This product is soluble in water, slightly soluble in ethanol and insoluble in chloroform.
Category: Pharmaceutical Raw Materials
Fields: β-Lactam Antibiotics, Cephalosporins
Deferred Products: Cefotaxime Sodium for Injection
Use: Suitable for pneumonia caused by sensitive bacteria and other lower respiratory infections, urinary tract infections, meningitis, sepsis, abdominal infections, pelvic infections, skin and soft tissue infections, reproductive tract infections, bone and joint infections, etc.

 

What is Cefotaxime?

Cefotaxime is an antibiotic used to treat a number of bacterial infections. Specifically it is used to treat joint infections, pelvic inflammatory disease, meningitis, pneumonia, urinary tract infections, sepsis, gonorrhea, and cellulitis. It is given either by injection into a vein or muscle.

 

Cefotaxime sodium certificate of Analysis

Product name Cefotaxime sodium
CAS No. 64485-93-4 Outer Packing 6kg/aluminum can
Production date 2018.03.10 Shelf life 2020.03.09
Standard adopted Enterprise standard
Items of analysis Specification Results
Character White or slightly yellow crystalline powder, White powder
Specific rotation +58°~+64° +59.71°
Absorption coefficient 360-390(235nm) 386.0
Identification    
PH 4.5-6.5 5.46
Solution Clarity <1# 0.5#(-)
Solution color ≤ yellow or yellow-green or orange yellow 5 3YG(-)
Insoluble particles ≥10um particles must not exceed 3000 particles/1g, ≥25um particles must not exceed 300 particles/1g 113 capsules/1 g; 19.3 capsules/1 g
Visible foreign objects ≤5 conforms
Moisture ≤2.6% 2.21%
Single impurity ≤0.8% 0.29%
Total impurities ≤2.5% 1.31%
Polymer ≤0.4% 0.09%
Methanol ≤0.3% 0.05%
Ethanol ≤0.5% 0.08%
Acetone ≤0.5% 0.39%
Isopropanol ≤0.5% 0.005%
Dichloromethane ≤0.06% 0.003%
Ethyl acetate ≤0.5% 0.002%
Tetrahydrofuran ≤0.072% 0.003%
Triethylamine ≤0.02% 0.0007%
Bacterial endotoxin <0.025EU/1mg <0.025EU/1mg
Assay Cefotaxime no less than 92% 93.8%
Conclusion Qualified

 

Cefotaxime Side Effects

Common side effects include nausea, allergic reactions, and inflammation at the site of injection. Other side effects may include inflammation at the site of injection and Clostridium difficile diarrhea.

It is not recommended in people who have had previous anaphylaxis to a penicillin. It is relatively safe for use during pregnancy and breastfeeding.

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