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Clozapine (Clozaril) Powder Raw Atypical Antipsychotic Medication

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Buy Clozapine (Clozaril) Powder Raw Atypical Antipsychotic Medication Online CAS 5786-21-0

 

Clozapine Specification

Product Name: Clozapine
CAS: 5786-21-0
Level: Medical grade
Content: 99%
Appearance: white powder
Packing: 25kg/cardboard drum detachable
Ingredients: For direct export only
Physical and chemical properties: Light yellow crystalline powder. Melting point 183-184 ° C. Soluble in chloroform, soluble in ethanol, almost insoluble in water. Odorless, tasteless.
Category: Pharmaceutical raw materials
Area: Antipsychotic drugs
Use: Control the mental illusion, delusion and excitement, the effect is better, so it can be used for excitement and incitement to patients, generally 4 to 5 days effective
Dosage: Oral Starting from a small dose, the first dose is 25mg once a day, 2~3 times a day, gradually increasing to 200~400mg per day for a common therapeutic dose, and the high dose can reach 600mg a day. The maintenance amount is 100~200mg per day.

 

What is Clozapine?

Clozapine, sold under the brand name Clozaril among others, is an atypical antipsychotic medication. It is mainly used for schizophrenia that does not improve following the use of other antipsychotic medications. In those with schizophrenia and schizoaffective disorder it may decrease the rate of suicidal behavior. It is more effective than typical antipsychotics and effective for those who are treatment resistant. It is taken by mouth.

 

Clozapine Certificate of Analysis

Product name Clozapine
CAS No. 5786-21-0 Outer Packing 25kg/drum
Production date 2018.3.23 Shelf life 2020.3.22
Standard adopted BP2012
Items of analysis Specification Results
Appearance Yellow crystalline powder Yellow crystalline powder
Solubility Practically insoluble in water,freely soluble in methylene chloride,soluble in ethanol(96per cent).It dissolves in dilute acetic acid. Conforms
Melting Point 182~186℃ 183.0~185.5℃
By IR The same as Ref.Standard Conforms
Impurity A ≤0.1% ND
Impurity B ≤0.2% 0.01%
Impurity C ≤0.3% 0.01%
Impurity D ≤0.2% ND
Unspecified Impurity ≤0.1% 0.01%
Total Impurity ≤0.6% 0.02%
Heavy metal ≤0.002% 〈0.002%
Loss on drying ≤0.5% 0.04%
Sulfate ash ≤0.1% 0.04%
Toluene ≤0.089% ND
Etjanol ≤0.5% 0.03%
Assay 99.0~101.0% 99.9%
Conclusion Qualified

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