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Dextran 40 Powder Pharmaceutical Raw Materials

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Buy Dextran 40 Powder Pharmaceutical Raw Materials Online CAS 9004-54-0

 

Dextran 40 Specification

Product Name: Dextran 40
CAS: 9004-54-0
Level: Medical grade
Molecular weight: molecular weight 32000~42000
Appearance: white powder
Packing: 25/ cardboard drum detachable
Category: Pharmaceutical raw materials
Area: Nutrition Enhancers
Deferred product: Dextran 40 Sodium Chloride Injection
Use: Expand blood volume, reduce blood viscosity and improve microcirculation.
Dosage: 1. Intravenous infusion, the dosage depends on the condition, the amount of adult commonly used once 250 ~ 500ml, within 24 hours does not exceed 1,000 ~ 1,00 ml. The amount of the baby is 5 ml/kg, and the amount of the child is 10 ml/kg. 2. Shock cases: the dosage can be larger, the speed can be faster, the infusion rate is 20 ~ 40ml / min, the maximum dose can be used to 20ml / kg on the first day, the dehydration must be corrected before use. 3. Prevention of postoperative thrombosis: 500ml during or after surgery, usually 500ml / day on the first and second day after surgery, intravenous infusion at a rate of 2 to 4 hours, high-risk patients, the course of treatment can be used up to 10 days. 4. Vascular embolism disease: should be slowly intravenous infusion, generally 250 ~ 500ml each time, daily or every other day, 7 to 10 times for a course of treatment.

 

What is Dextran?

Dextran is a complex branched glucan (polysaccharide made of many glucose molecules) composed of chains of varying lengths (from 3 to 2000 kilodaltons).

Medicinally it is used as an antithrombotic (antiplatelet), to reduce blood viscosity, and as a volume expander in hypovolaemia. Dextran 70 is on the WHO Model List of Essential Medicines, the most important medications needed in a health system.

 

Dextran 40 Certificate of Analysis

Product name Dextran 40
CAS No. 9004-54-0 Outer Packing 25kg/drum
Production date 2017.12.2 Shelf life 2020.12.1
Standard adopted CP2015Edition 2
Items of analysis Specification Results
Character White powder; odorless. Soluble in hot water, insoluble in ethanol Conforms
Specific rotation +190°~+200° +193°
Identification Positive response Conforms
Chloride ≤0.25% <0.12%
Nitrogen ≤0.007% <0.007%
Loss on drying ≤5.0% 2.2%
Burning residue ≤0.5% 0.2%
Heavy metal ≤8ppm <8ppm
Molecular weight and distribution MW: 32000~42000 37009
Molecular weight and distribution M10≤120000 108491
Molecular weight and distribution M90≥5000 7537
Conclusion Qualified

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