Raw Local Anesthetic Powder Dibucaine Hydrochloride/ Dibucaine HCl for Relieving Pain
What is Dibucaine Hydrochloride?
Dibucaine hydrochloride is a local anesthetic of the amide type now generally used for surface anesthesia. It is one of the most potent and toxic of the long-acting local anesthetics and its parenteral use is restricted. The drug blocks both the initiation and conduction of nerve impulses by decreasing the neuronal membrane’s permeability to sodium ions. It is one of the most potent and toxic of the long-acting local anesthetics and its parenteral use is restricted to spinal anesthesia.
Dibucaine Hydrochloride Basic Info
Alias: Dibucaine Hcl
CAS: 61-12-1
MF: C20H30ClN3O2
MW: 379.92
Appearance: White crystalline Powder
Assay: 99%
Purpose:The products for epidural anesthesia, spinal anesthesia and local anesthesia.
Package:1kg/bag;25kg/drum.
Dibucaine Hydrochloride Certificate Of Analysis
Product name |
DIBUCAINE HCL(CINCHOCAINE HCL) |
CAS No. |
61-12-1 |
Outer Packing |
1kg/bag |
Production date |
2018.01.02 |
Shelf life |
2020.01.01 |
Standard adopted |
USP35 |
Items of analysis |
Specification |
Results |
Characters |
A white or almost white crystalline powder |
complies |
Identification |
IR/UV |
Complies |
Solubility |
Freely soluble in water,in alcohol, in acetone, and in chloroform |
Complies |
Loss on drying |
≤2.0% |
0.97% |
Residue on ignition |
≤0.1% |
0.02% |
PH |
About 5.5 |
5.39 |
Chromatographic purity |
the sum of the intensities of any secondry spots,if present in the chromatogram of the test solution,correspunds to not more than 1.0%and the intensity of any secondary spot does not exceed 0.5% of that of the principal spot in chromatogram of standard solution |
Complies |
Residual solvents |
Should be to match with the standard |
Complies |
Assay |
97.0% ~ 100.5% |
99.86% |
Conclusion |
Qualified |
Dibucaine Hydrochloride Application
For production of local or regional anesthesia by infiltration techniques such as percutaneous injection and intravenous regional anesthesia by peripheral nerve block techniques such as brachial plexus and intercostal and by central neural techniques such as lumbar and caudal epidural blocks. Dibucaine Hydrochloride is an amide-type local anesthetic, similar to lidocaine.
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