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Econazole Nitrate Powder Raw Antifungal Medication Drug

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Buy Econazole Nitrate Powder Raw Antifungal Medication Drug Online CAS 68797-31-9

 

Econazole Nitrate Specification

Product Name: Econazole Nitrate
CAS: 68797-31-9
Standard: USP36
Content: 99%
Appearance: white powder
Number of meshes:80
Packing: 25KG/cardboard drum
Ingredients: (±)-1-[2,4-Dichloro-β-(4-chlorobenzyloxy)phenethyl]imidazolium nitrate Potentiometric titration
Physicochemical properties: white to yellowish crystalline or crystalline powder; odorless. This product is soluble in methanol, slightly soluble in chloroform, very slightly soluble in water. Melting point 163~167°C, simultaneous decomposition when melting
Category: Pharmaceutical Raw Materials
Field: Anti-Skin Candidiasis
Deferred product: econazole nitrate 1% spray
Use: for the treatment of cutaneous candidiasis; can also be used to treat body tinea, jock itch, athlete’s foot, tinea versicolor, etc.
Dosage: topical, spray on the affected area, 2 times a day; tinea versicolor, treatment for 2 weeks; other tinea and skin candidiasis, treatment for 2 to 4 weeks

 

What is Econazole?

Econazole (commonly used as the nitrate salt) is an antifungal medication of the imidazole class. It is a component of Pevisone and Ecoderm-TA(econazole/triamcinolone).

 

Econazole Nitrate Certificate of Analysis

Product name Econazole Nitrate
CAS No. 24169-02-6;68797-31-9 Outer Packing 25kg/Drum
Production date 2016.06.06 Shelf life 2019.06.05
Standard adopted USP36
Items of analysis Specification Results
Appearance White or almost white powder Complies
Identification IR Similar To Standard
Appearance of Solution The solution is clear and not more intensely cloured than reference solutions Y7 Complies
Solubility Very slightly soluble in water;soluble in methanol;slightly soluble in alcohol Complies
Angle of optical rotation -0.1°—— +0.1°
Each Impurity ≤0.2% 0.15%
Total Impurity ≤0.3% 0.26%
Melting Point 163-167℃ 164.8-165.9℃
Loss On Drying ≤0.5% 0.24%
Sulphated Ash ≤0.1% 0.06%
Toluene ≤890ppm 120ppm
Ethanol ≤600ppm 100ppm
Assay(On Dry Basis) 99~101% 99.3%
Conclusion Qualified

 

Econazole Nitrate Medical uses

Econazole is used as a cream to treat skin infections such as athlete’s foot, tinea, pityriasis versicolor, ringworm, and jock itch.

Econazole nitrate exhibits strong anti-feeding properties against the keratin-digesting common clothes moth Tineola bisselliella.

 

Econazole Nitrate Side Effects

The most common symptoms were burning, itching, erythema, and one outbreak of a pruritic rash

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