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Irbesartan Powder Raw Angiotensin II Receptor Antagonist Drug for Hypertension

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Buy Irbesartan Powder Raw Angiotensin II Receptor Antagonist Drug for Hypertension Online CAS 138402-11-6

 

Irbesartan Specification

Product Name: Irbesartan
CAS: 138402-11-6
Level: Medical grade
Content: 99%
Appearance: white powder
Packing: 25kg/cardboard drum
Category: Pharmaceutical Raw Materials
Field: Antihypertensive drugs
Deferred Products: Blood Pressure Lowering Drugs
Use: Lower blood pressure, treatment of essential hypertension
Usage and dosage: Oral: Recommended starting dose is 0.15g, once a day. According to the condition can be increased to 0.3g, once a day. It can be used alone or in combination with other antihypertensive drugs.

 

What is Irbesartan?

Irbesartan is an angiotensin II receptor antagonist used mainly for the treatment of hypertension.

 

Irbesartan Certificate of Analysis

Product name Irbesartan
CAS No. 138402-11-6 Outer Packing 25kg/drum
Production date 2017-7-28 Shelf life 2020-06
Standard adopted USP38
Items of analysis Specification Results
Appearance White to off white crystalline powder off White crystalline powder
Solubility Slightly soluble in ethanol and dichloromethane, almost insoluble in water Conforms
Identification This product’s infrared absorption spectrum should be consistent with the reference map Conforms
Identification The retention time of the main peak of the test solution should be the same as the retention time of the main peak of the reference solution. Conforms
Water ≤0.5% 0.3%
Sarcophosphate ≤10ppm 1ppm
Heavy metal ≤0.002% <0.002%
relative substance Related substances A≤0.2% 0.05%
Relative substance Other single impurities ≤ 0.1 0.02%
relative substance Total mpurities ≤ 0.1 0.11
Assay 98%-102% 99.3%
Toluene ≤890ppm 29ppm
Dichloromethane ≤600ppm 30ppm
N,N-Dimethylformamide ≤880ppm 11ppm
Ethanol ≤5000ppm 19ppm
Conclusion Qualified

 

Irbesartan Application

Irbesartan is used to treat high blood pressure (hypertension) and to help protect the kidneys from damage due to diabetes. Lowering high blood pressure helps prevent strokes, heart attacks, and kidney problems. Irbesartan belongs to a class of drugs called angiotensin receptor blockers (ARBs). It works by relaxing blood vessels so that blood can flow more easily.

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