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Levocetirizine Dihydrochloride (Xyzal) Powder | Non-sedating Antihistamine APIs

» Pharmaceutical » Respiratory System APIs » Levocetirizine Dihydrochloride (Xyzal) Powder | Non-sedating Antihistamine APIs

  • Specifications

Buy Non-sedating Antihistamine APIs Levocetirizine Dihydrochloride (Xyzal) Powder Online

 

What is Levocetirizine dihydrochloride?

Levocetirizine (as levocetirizine dihydrochloride) is a third-generation, non-sedating antihistamine, developed from the second-generation antihistamine cetirizine. Chemically, levocetirizine is simply the isolated levorotary enantiomer of cetirizine, which is sold as a racemic mixture.

 

Levocetirizine dihydrochloride Basic Information

Product Name: Levocetirizine dihydrochloride;
Synonyms: LEVOCETIRIZINE 2HCL;LEVOCETIRIZINE DIHCL;LEVOCETIRIZINE DIHYDROCHLORIDE;LEVOCETIRIZINE HCL;LEVOCETRIZINE DIHYDROCHLORIDE;[2-[4-[(r)-(4-chlorophenyl)phenylmethyl]-1-piperazinyl]ethoxy]-acetic acid dihydrochloride;LevocetrizineHCl;LEVOCITIRIZINE DIHYDROCHLORIDE;
CAS: 130018-87-0;
MF: C21H27Cl3N2O3;
MW: 461.81;
EINECS: 200-659-6;
Product Categories: API’s; Levocetirizine; Histamine receptor; API; Levocitirizine 2HCl;Antibiotics;
Melting point: 215-220°C;
storage temp.: room temp;
Purity:99%
Apperance:white powder

 

Levocetirizine dihydrochloride certificate of analysis

Product name Levocetirizine dihydrochloride
CAS No. 130018-87-0 Outer Packing 1kg/bag
Production date 15th Jan 2018 Shelf life 14th Jan 2020
Standard adopted Enterprise Standard
Items of analysis Specification Results
appearance white to off white solid off white solid
solubility soluble in water and methanol complies
identification
A.IR Spectrum match with structure complies
B NMR Spectrum
I 1HNMR match with structure complies
II 13 CNMR match with structure complies
C Mass spectrum match with theoretical mol.wt of compound complies
loss on drying not more than 0.5% w/w 0.20% w/w
sulphated ash not more than 0.1% w/w 0.03% w/w
related substances by HPLC
single max.impurity not more than 0.10% 0.03%
total impurities not more than 0.50% 0.07%
enantiomeric purity not less than 99.50% 99.83%
potency by mass balance 98.0%w/w to 102.0% w/w 99.90% w/w
Conclusion Qualified

 

Levocetirizine dihydrochloride Medical uses

Levocetirizine is used for allergy symptoms including watery eyes, runny nose, sneezing, hives, and itching.

 

Levocetirizine dihydrochloride side effects

Levocetirizine is called a non-sedating antihistamine as it does not enter the brain in significant amounts, and is therefore unlikely to cause drowsiness.

However, some people may experience some slight sleepiness, headache, mouth dryness, lightheadedness, vision problems (mainly blurred vision), palpitations and fatigue

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