Buy EP5 Levodropropizine Powder For Sale from China Manufacturer Source (CAS 99291-25-5)
What is Levodropropizine?
Levodropropizine is a cough suppressant. It is the levo isomer of dropropizine. It acts as a peripheral antitussive, with no action in the central nervous system. It does not cause side effects such as constipation or respiratory depression which can be produced by opioid antitussives such as codeine and its derivatives.
Levodropropizine Basic Information
| Product Name |
Levodropropizine |
| CAS number |
99291-25-5 |
| Molecular formula |
C13H20N2O2 |
| Molecular weight |
340.37816 |
| Appearance |
White or off white crystalline powder |
| Melting Point |
102-106ºC |
| Relative density |
1.168g/cm3 |
Levodropropizine Certificate of Analysis
| Product name |
Levodropropizine |
| CAS No. |
99291-24-4 |
Packing |
25kg/Drum |
| Production date |
15th Jan 2018 |
Shelf life |
15th Jan 2021 |
| Standard adopted |
EP5 |
| Items of analysis |
Specification |
Results |
| Appearance |
White or almost white power |
Pass |
| Identification A |
Between -30.0 to -33.5 |
-31.2 |
| Identification B |
IR. As stipulation |
Pass |
| pH |
9.2-10.2 |
9.6 |
| Impurity B |
No more than 0.5% |
0.13% |
| Related substance |
As stipulation |
Pass |
| Impurity C |
Not more than 100ppm |
Pass |
| Enantiomeric purity |
Not more than 2.0% |
0.48% |
| Loss on drying |
Not more than 1.0% |
0.35% |
| Sulphated ash |
Not more than 0.2% |
0.05% |
| Assay |
Between 98.5% and 101.0% |
99.55% |
| Conclusion |
Qualified |
Levodropropizine Benefits
levodropropizine is an effective antitussive drug in children and adults, with statistically significant better overall efficacy outcomes vs. central antitussive drugs (codeine, cloperastine, dextromethorphan) in terms of reducing cough intensity and frequency, and nocturnal awakenings. This result further reinforces the favorable benefit/risk profile of levodropropizine in the management of cough. The efficacy of levodropropizine in the treatment of cough in children and adults is higher than that of the common centrally-acting anti-tussive.
Levodropropizine Indications:
Levodropropizine is used for the treatment of non-productive cough.It acts on the lungs and suppresses the cough by reducing the cough reflex.
Levodropropizine Side effects
Acne-like rash, Chest pain, Dizziness, Nausea, Insomnia, Gastric pain, Headache and palpitations
