China Topical Local Anesthetic Powder Pramoxine Hydrochloride Hcl CAS 637-58-1 For Sale
What is Pramoxine Hydrochloride?
Pramocaine (INN and BAN, also known as pramoxine or pramoxine HCI) is a topical anesthetic used as an antipruritic. Chemically, it is p-n butoxyphenyl gammamorpholinopropyl ether hydrochloride.
During research and development, pramoxine hydrochloride stood out among a series of alkoxy aryl alkamine ethers as an especially good topical local anesthetic agent.Pharmacologic study revealed it to be potent and of low acute and subacute toxicity, well tolerated by most mucous membranes and of a low sensitizing index in humans. Like other local anesthetics, paramoxine decreases the permeability of neuronal membranes to sodium ions, blocking both initiation and conduction of nerve impulses. Depolarization and repolarization of excitable neural membranes is thus inhibited, leading to numbness.
Pramoxine Hydrochloride Basic Info
CAS:637-58-1
Suitable for:Elderly, Adult
Purity:>99%
Origin:China
Powder:Yes
Certification:ISO 9001
State:Solid
Appearance:White Crystalline Powder
Customized:Non-Customized
M.F.:C17h28clno3
MW:329.86
EINECS:211-293-1
Pramoxine Hydrochloride Certificate Of Analysis
| Product |
Pramoxine Hydrochloride |
| Tests |
Results |
Specifications |
| Description |
White crystalline powder |
White to almost white crystalline powder |
| Solubility |
Complies |
Freely soluble in water and in alcohol ,soluble in chloroform,very slightly soluble in ether |
| PH |
4.37 |
About 4.5 |
| IdentifIcation |
Complies |
A: By IR, To match with working standard |
| Complies |
B:By HPLC, To match with working standard |
| Complies |
C: A solution responds to the test for Chloride |
| Melting point |
172.6℃～173.5℃ |
170℃～174℃ |
| Loss on drying |
0.18% |
≤1.0% |
| Residue on ignition |
0.03% |
≤0.1% |
| Residual Solvents |
Not detected |
Toluene ≤0.089% |
| Not detected |
Ethanol ≤0.5% |
| 0.003% |
Petroleum ether ≤0.5% |
| 0.009% |
Acetone ≤0.5% |
| 0.006% |
Methanol ≤0.3% |
| Assay |
99.96% |
98.0%-102.0%(on the anhydrous basis) |
| Conclusion: Conforms to USP36 |
Pramoxine Hydrochloride Application
Topical anesthetics are used to relieve pain and itching caused by conditions such as sunburn or other minor burns, insect bites or stings, poison ivy, poison oak, poison sumac, and minor cuts and scratches. Pramocaine and dibucaine are also common ingredients in over the counter hemorrhoid preparations.
Buy Pramoxine Hydrochloride Powder
1. Minimum order quantity(MOQ): 10g
2. Payment way: Money Gram, Western Union, Bank Transfer and Bitcoin
3. Lead Time: Within 12hours after you payment
4. Delivery Time: 3-7 days door to door
5. Packing: Super discreet (hundreds to choose from)
6. Shipping: DHL / TNT / UPS / HKEMS / FedEx / etc.
7. Tracking number: Available after parcel deliver out.
8. After-sales service: 24/7 online
