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Mebendazole Powder Benzimidazole Type Broad-spectrum Antihelminthic Agent

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Buy Mebendazole Powder Benzimidazole Type Broad-spectrum Antihelminthic Agent Online CAS 31431-39-7

 

Mebendazole Specification

Product Name: Methylimidazole
CAS: 31431-39-7
Standard: USP
Level: Medical grade
Content: 99%
Appearance: White powder
Packing: 25 kg / plastic bucket Detachable
Ingredients: Mebendazole 99
Physical and chemical properties: White to light yellow crystalline powder, odorless, tasteless. The temperature of 288.5 ° C. Soluble in formaldehyde, formic acid, glacial acetic acid and bitter almond oil, insoluble in water. Not hygroscopic, stable in the air.
Category: Pharmaceutical raw materials
Application: Anthelmintic, an effective broad-spectrum anthelmintic drug for the treatment of mites, mites, whip, mites, hooks, and roundworms.
Dosage: Treatment of aphids, hookworms, whipworm disease: 5ml once, 2 times a day, and even served for 3 days. The drug was administered once every 2 weeks and 4 weeks.

 

What is Mebendazole?

Mebendazole (MBZ) is a medication used to treat a number of parasitic worm infestations. This includes ascariasis, pinworm disease, hookworm infections, guinea worm infections, hydatid disease, and giardia, among others. It is taken by mouth.

 

Mebendazole Certificate of Analysis

Product name Mebendazole
CAS No. 31431-39-7 Outer Packing 25kg/drum
Production date 2017.11.20 Shelf life 2022.11.19
Standard adopted USP 36
Items of analysis Specification Results
Description white to slight yellow powder amorphous,powder almost odorless,it shows polymorphism slight yellow powder almost odorless,it shows polymorphism
solubility practically insoluble in water,in dilute solution of mineral acid in alcohol,in ether and chloroform,freely soluble in formic acid complies
identification(IR) the IR spectrum of the sample should be concordant with the standard spectrum of the mebendazole W.S. complies
melting point melt at about 290℃ complies
loss on drying dry at 105℃ for 4 hours not more than 0.5% w/w 0.30%
inorganic impurities as per USP 36 complies
1.residue on ignition not more than 0.10% 0.072%
2.heavy metals not more than 0.002% complies
organics impurities chromatographic purity the Rf value of the principal spot of the solution corresponds to that of the standard stock solution,and no spot other than the principal spot of the sample solution is larger or more intense than the principal spot of the diluted standard solution complies
assay 98%-102% 100.07% w/w
residual solvent as per USP complies
1.methanol NMT 3000ppm complies
2.N,N,DMF NMT 880ppm ND
3.acetic acid NMT 5000ppm ND
particle size 90%<75.0 microns complies
Conclusion Qualified

 

Mebendazole Side Effects

Mebendazole is usually well tolerated. Common side effects include headache, vomiting, and ringing in the ears. If used at large doses it may cause bone marrow suppression. It is unclear if it is safe in pregnancy. Mebendazole is a broad-spectrum antihelminthic agent of the benzimidazole type.

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