Buy Phenformin Hydrochloride Powder Biguanide Class Antidiabetic Drug Online
What is Phenformin Hydrochloride
Phenformin hydrochloride is a white crystalline powder, with a melting point of 175 to 178 °C; it is soluble at 1 in 8 parts of water and 1 in 15 of ethanol, and practically insoluble in chloroform and ether.[citation needed] Phenformin is less polar and more lipid soluble and exhibits a higher affinity for mitochondrial membranes than metformin.[8] Its dissociation constant (pKa) is 2.7, 11.8 (at 32 °C), and partition coefficient (log P in octanol/water) = –0.8.[citation needed]
Phenformin is an antidiabetic drug from the biguanide class.
Phenformin Hydrochloride Specification
| Product name |
Phenformin hydrochloride |
| Synonyms |
1-Phenethylbiguanide hydrochloride |
| CAS No. |
834-28-6 |
| EINECS |
212-637-3 |
| Molecular formula |
C10H15N5.HCl;C10H16ClN5 |
| Molecular weight |
241.72 |
| Appearance |
White powder |
| Melting point |
175-178 ºC |
| Assay |
99% |
| Packing |
25Kg/drum |
| Application |
Phamaceutical Intermediates |
More details about Phenformin
Phenformin is well absorbed after oral administration. The major metabolic reaction is aromatic hydroxylation to form 4–hydroxyphenformin, which is then conjugated with glucuronic acid. Up to about 50% of a dose is excreted in the urine in 24 h, about two–thirds in the form of unchanged drug and one–third as the hydroxy metabolite.
