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Rifabutin (Rfb) Powder Raw Antibiotic Drug For Tuberculosis

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  • Specifications

Buy Rifabutin (Rfb) Powder Raw Antibiotic Drug For Tuberculosis Online CAS 72559-06-9

 

Rifabutin Specification

Product Name: Rifabutin
CAS: 72559-06-9
Content: 99%
Appearance: white powder
Packing: 25/iron drum
Ingredients: rifabutin
Physical and chemical properties: purple red crystalline powder. Easily soluble in chloroform
Category: Pharmaceutical Raw Materials
Industry: Pharmaceuticals
Field: Pharmaceutical raw materials
Down products: rifabutin granules, capsules
Application: Pulmonary infections for mycobacteria, also effective against rifampin-resistant Mycobacterium tuberculosis strains
Dosage: Oral, 150mg~300mg per serving, 1~2 times daily

 

What is Rifabutin?

Rifabutin (Rfb) is an antibiotic used to treat tuberculosis and prevent and treat Mycobacterium avium complex.

 

Rifabutin Certificate of Analysis

Product name Rifabutin
CAS No. 72559-06-9 Outer Packing 25kg/drum
Production date 2018.01.10 Shelf life 2 years
Standard adopted Enterprise standard
Items of analysis Specification Results
Description Purple-red to purple-black powder Purple-red powder
Solubility Soluble in methanol and chloroform, slightly soluble in ethanol, almost insoluble in water. Conform
Identification The retention time of major peak in the chromatogram of the assay preparation corresponds that in the chromatogram of standard preparation. Conform
N-Isobutylpiperidone Not more than 0.5% by TLC test Less than 0.3%
Assay Not less than 950 μg and not more than 1020 μg of C46H62N4O11 per mg, calculated on the anhydrous basis. 991 μg /mg
Conclusion Qualified

 

Rifabutin Application

It is typically only used in those who cannot tolerate rifampin such as people with HIV/AIDS on antiretrovirals. For active tuberculosis it is used with other antimycobacterial medications. For latent tuberculosis it may be used by itself when the exposure was with drug-resistant TB.

 

Rifabutin Side Effects

Common side effects include abdominal pain, nausea, rash, headache, and low blood neutrophil levels. Other side effects include muscles pains and uveitis.

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