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Telmisartan (Micardis) Powder Raw Angiotensin II Receptor Antagonist Drug

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  • Specifications

Buy Telmisartan (Micardis) Powder Raw Angiotensin II Receptor Antagonist Drug Online CAS 144701-48-4

 

Telmisartan Specification

Product Name: Telmisartan
CAS: 144701-48-4
Standard: EP
Natural / Synthetic: Synthetic
Level: Medical grade
Content: 99%
Appearance: white powder
Packing: 25KG/ cardboard drum detachable
Category: Pharmaceutical raw materials
Field: Pharmaceutical raw materials
Deferred product: telmisartan tablets, telmisartan capsules
Use: Treatment of essential hypertension
Dosage: Adult: 40mg—80mg once a day. The time of taking is not affected by the diet. Patients with mild or moderate renal dysfunction, as well as elderly people do not need to adjust the dose to take this product. For patients with mild or moderate hepatic insufficiency, the dosage should not exceed 40 mg/day. For children: The safety and efficacy data for this product has not been established.

 

What is Telmisartan?

Telmisartan is an angiotensin II receptor antagonist (angiotensin receptor blocker, ARB) used in the management of hypertension.

 

TELMISARTAN Certificate of Analysis

Product name TELMISARTAN
CAS No. 144701-48-4 Outer Packing 25KG/drum
Production date 2018-5-30 Shelf life 2020-5-29
Standard adopted EP7.0
Items of analysis Specification Results
Appearance

 

White or slightly yellowish,crystalline powder Conform

 

Solubility Insoluble water,slightly soluble in methanol,sparingly soluble in methylene chloride.It dissolves in 1M sodium hydroxide. Conform
IDENTIFICATION
A Infra-red absorption spectrum should be identical with contrast. Contorm

 

TESTS
Appearance of solution Dissolve 0.5g in 1M sodium hydroxide and dilute to 10ml with the same solvent:NMT Y4 Contorm

 

Related substances Impurities C:NMT 0.2% Unfound
Related substances Impurities D:NMT 0.2% 0.04%
Related substances Impurities A:NMT 0.15% 0.005%
Related substances Impurities B:NMT 0.15% 0.006%
Related substances Unspecified impurities:NMT 0.1% 0.05%
Related substances Total impurities:NMT 1.0% 0.27%
Loss on drying NMT 0.5% 0.5%
Sulphated ash NMT 0.1% 0.05%
Residual Solvents Methanol:NMT 3000ppm Unfound
Residual Solvents 1,2-dimethoxyethane:NMT 100ppm Unfound
Residual Solvents Ethanol:NMT 5000ppm Unfound
Residual Solvents Acetic acid:NMT 5000ppm Unfound
ASSAY 99.0%~101.0% 100.0%
Conclusion Qualified

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