Buy Tenofovir Disoproxil Fumarate Raw Drug For HIV Infection Treatment CAS 202138-50-9
Tenofovir disoproxil fumarate Sepcification
Product Name: Tenofovir disoproxil fumarate
CAS:202138-50-9
Standard: Corporate Standard
Level: Pharmaceutical grade
Content: 99%
Appearance: white powder
Packing: 25KG/cardboard drum
Ingredients: 9-((R)-2-((bis(((isopropoxycarbonyl)oxy(methoxy)phosphinyl)-propyl)adenine fumarate
Physicochemical properties: white or almost white crystalline powder; odorless. Soluble in dimethylformamide, soluble in methanol; slightly soluble in water, acetonitrile
Category: Pharmaceutical Raw Materials
Field: Antiviral drugs
Deferred product: Tenofovir disoproxil fumarate tablets
Application: For the treatment of human immunodeficiency virus (HIV) infection
What is tenofovir disoproxil fumarate?
Tenofovir DF is a prescription medicine approved by the U.S. Food and Drug Administration (FDA) for the treatment of HIV infection in adults and children 2 years of age and older. Tenofovir DF is always used in combination with other HIV medicines.
Tenofovir DF belongs to a class (group) of HIV drugs called nucleoside reverse transcriptase inhibitors (NRTIs). NRTIs block an HIV enzyme called reverse transcriptase. (An enzyme is a protein that starts or increases the speed of a chemical reaction.) By blocking reverse transcriptase, NRTIs prevent HIV from multiplying and can reduce the amount of HIV in the body.
Tenofovir disoproxil fumarate Certificate Of Analysis
| Product name |
Tenofovir disoproxil fumarate |
| CAS No. |
202138-50-9 |
Outer Packing |
25KG |
| Production date |
2017.04.20 |
Shelf life |
2019.04.19 |
| Standard adopted |
ENTERPRISE STANDARD |
| Items of analysis |
Specification |
Results |
| Appearance |
White to off-white crystalline powder |
white crystalline powder |
| Solubility |
Freely soluble in the methanol and in dimethyl form anmmide;sparingly soluble in water |
conforms |
| Identifcation |
By IR /HPLC |
conforms |
| Water(ByK.F) |
NMT 1.0% |
0.44% |
| Fumaric acid |
17.5-19% |
18.30% |
| Heavy metal |
≤0.002% |
conforms |
| Tenofovir |
≤0.15% |
0.08% |
| Tenofovir isoproxil monoester |
≤0.8% |
0.28% |
| Tenofovir isopropyl isoproxil |
≤0.15% |
conforms |
| Desmethyl isopriopyl disproxil |
≤0.15% |
conforms |
| Specified unidentified impurity at RRT1.05(molecular weight 541) |
≤0.15% |
conforms |
| Any individual unspecified impurity |
≤0.1% |
0.05% |
| Total impurites |
≤1.0% |
0.38% |
| Chloromethy isopropyl carbonate By GC |
≤0.15% |
conforms |
| Enantiomeric purity By HPLC |
≤1.0% |
conforms |
| 9-Propenyladenine By HPLC |
5ppm |
ND |
| Isopropyl alcohol |
≤3000ppm |
conforms |
| Dichloromethane |
≤300ppm |
conforms |
| Isopropyl acetate |
≤4000ppm |
conforms |
| N-methyl pyrrolidone |
≤480ppm |
conforms |
| Total residual solvents |
≤7780ppm |
conforms |
| Assay(on the anhydrous) |
98-102% |
99.62% |
| Conclusion |
Qualified |
