Buy EP Terbinafine Hydrochloride (Terbinafine hcl) Powder Raw fungal infections Drug Online CAS 78628-80-5
Terbinafine Hydrochloride Specification
Product Name: Terbinafine Hydrochloride
CAS: 78628-80-5
Standard: EP
Content: 99%
Appearance: white powder
Packing: 25KG/cardboard drum
Ingredients: (E)-N-(6,6-Dimethyl-2-heptene-4-yne)-N-methyl-1-naphthylamine hydrochloride Any unknown impurity ≤0.1% Total impurities: ≤0.3%
Physicochemical properties: white crystalline powder Molecular formula: C21H26ClN Molecular weight: 327.89 Melting point: 204-208°C Boiling point: 417.9°C Flash point: 183.7°C Solubility: Soluble in methanol, dissolved in ethanol or chloroform, slightly soluble in propylene glycol, Slightly soluble in water.
Category: Pharmaceutical Raw Materials
Field: Allylamine antifungal drugs
Deferred Products: Tablets Solutions, Gels, Ointments Sprays Suppositories
Application: It can be used to treat Trichophyton (Trichophyton rubrum, Trichophyton mentagrophytes, Trichophyton rubrum, Trichophyton spp. and Trichophyton rubrum, etc.), Microsporidia canis and Epidermophyton floccosum etc. The infection of the skin, hair and nails. It can also treat a variety of rickets (body lice, tinea cruris, tinea pedis and tinea capitis, etc.) as well as skin yeast infections caused by Candida (Candida albicans, etc.), and onychomycosis caused by mold (bacterial infections) )
Usage and dosage: tablets for oral use, solutions, gels, ointments and other external preparations for skin coating only. When taking orally, each adult 0.25g, once a day, depending on the degree of infection, the general body and jock itch treatment for 2-4 weeks, hand and foot sputum 2-6 weeks, cutaneous candidiasis 2-4 weeks, Head lice 4 weeks, hyperthyroidism 6 weeks – 3 months. For external use, the affected area will be applied in appropriate amounts and around it twice a day. The course of treatment depends on the degree of infection. The general body and tinea cruris are 2-4 weeks. The hand, foot and tinea pedis are 4-6 weeks. Proper treatment time can be extended. Tablets taken orally are not effective against tinea versicolor.
What is Terbinafine?
Terbinafine is used to treat certain types of fungal infections (e.g., fingernail or toenail). It works by stopping the growth of fungus. This medication belongs to a class of drugs known as antifungals.
Terbinafine Hydrochloride Certificate of Analysis
| Product name |
Terbinafine Hydrochloride |
| CAS No. |
78628-80-5 |
Outer Packing |
2016.06.24 |
| Production date |
2018.02.09 |
Shelf life |
2020.02.08 |
| Standard adopted |
EP8.0 |
| Items of analysis |
Specification |
Results |
| Description |
White or almost white powder |
almost white powder |
| Solubility |
very slightly or slightly soluble in water, freely soluble in anhydrous ethanol and in methanol, slightly soluble in acetone |
Complies |
| Identification |
Infrared absorption spectrophotometry.Comparison: terbinafine hydrochloride CRS |
Complies |
| Identification |
It gives reaction (a) of chlorides using anhydrous ethanol R as solvent |
Complies |
| Impurity B |
≤0.15% |
Complies |
| unspecified impurities |
each Impurity not more than 0.1% |
Complies |
| Sum of impurity |
not more than 0.3% |
Complies |
| Loss on drying |
≤0.5% |
0.40% |
| Sulfated ash |
≤0.1% |
0.01% |
| ethyl acetate |
≤0.5% |
Complies |
| dichloromethane |
≤0.06% |
Complies |
| isopropanol |
≤0.5% |
Complies |
| Assay |
99.0%-101.0% |
99.88% |
| Conclusion |
Qualified |
Terbinafine Hydrochloride Side Effects
Common side effects when taken by mouth include nausea, diarrhea, headache, cough, rash, and elevated liver enzymes.
