100.4% Purity white Raw Local Anesthesic Agents powder Tetracaine Hydrochloride Hcl CAS136-47-0 For Sale
What is Tetracaine Hydrochloride?
Tetracaine hydrochloride is used as a local anaesthetic which acts by reversibly blocking the propagation and conduction of nerve impulses along nerve axons. Tetracaine stabilises the nerve membrane, preventing the increase in sodium permeability necessary for the production of an action potential.
Tetracaine is a potent local anesthetic of the ester group. It is mainly used topically in ophthalmology and as an antipruritic, and it has been used in spinal anesthesia.
Tetracaine Hydrochloride Basic Info
CAS: 136-47-0 Molecular formula: C15H25ClN2O2 Molecular Weight: 300.8242 Appearance: White crystalline powder Grade: Pharmaceutical Grade Usage: Local anesthetic; Mainly used in mucosa anesthetic. The function is stronger than Procaine and Lidocaine.
Tetracaine Hydrochloride Certificate Of Analysis
Items
QUALITY STANDARDS
RESULTS
Description
White or almost white crystalline powder
White crystalline powder
Solubility
Matching with the working standard
Complies
Identification
A.By IR, To match with working standard
Complies
B: To 10ml of solution S add 1ml of ammonium thiocyanate solution R.A white,crystalline precipitate is formed which,after recrystallisation from water R and drying at 80ºC for 2h,melts at about 131ºC
Complies
C. To about 5mg add 0.5ml of fuming nitric acid R .Evaporate to dryness on a water-bath,allow to cool and dissolve the residue in 5ml of acetone R.Add 1ml of 0.1M alcoholic potassium hydroxide.A violet colour develops
Complies
D. Solution S gives reaction of chlorides.
Complies
PH
4.5~6.5
5.78
Residual Solvents
Conform to standard
Complies
Claruty
Solution should be clear
Complies
Related Substances
Conform to standard
Complies
Heavy metals
≤10ppm
<10ppm
Loss on drying
≤1.0%
0.87%
Resiue on ignition
≤0.1%
0.05%
Melting range
148ºC
147.5ºC~150.8ºC
Assay(*)
99%~101.0%
100.40%
Conclusion
The Sample Complies With Specification of EP8
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