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Valsartan Powder Raw Hypertensive Drug

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Buy Valsartan Powder Raw Hypertensive Drug Online CAS 137862-53-4

 

Valsartan Specification

Product Name: Valsartan
CAS: 137862-53-4
Standard: USP
Level: Medical grade
Content: 99%
Appearance: white powder
Packing: 20KG/full cardboard drum detachable
Category: Pharmaceutical raw materials
Area: Hypertensive drugs
Use: Treatment of high blood pressure
Dosage: Recommended dosage: 80mg of this product, once a day. The dose has nothing to do with race, age or gender. It can be taken at mealtime or on an empty stomach (see Absorption). It is recommended to take the medicine at the same time every day (such as in the morning). The exact antihypertensive effect was achieved within 2 weeks of treatment, and the maximum effect was achieved after 4 weeks. When the antihypertensive effect is unsatisfactory, the daily dose can be increased to 160 mg, or a diuretic can be added. Patients with renal insufficiency (precautions for severe renal failure) and patients with non-biliary and non-cholestatic liver dysfunction do not need to adjust the dose. Valsartan can be combined with other antihypertensive drugs.

 

What is Valsartan?

Valsartan (Diovan) is mainly used for treatment of high blood pressure, congestive heart failure, and to increase the chances of living longer after a heart attack. It is an angiotensin II receptor antagonist (commonly called an ARB, or angiotensin receptor blocker), that is selective for the type I (AT1) angiotensin receptor.

 

Valsartan Certificate of Analysis

Product name Valsartan
CAS No. 137862-53-4 Outer Packing 25kg/drum
Production date 2017.04.21 Shelf life 2020.04.20
Standard adopted UPS
Items of analysis Specification Results
Character White or off-white powder, odorless, slightly hygroscopic Conforms
Solubility Soluble in methanol and ethanol, slightly soluble in ethyl acetate, slightly soluble in dichloromethane, almost insoluble in water Conforms
Identification IR, HPLC meets reference standards Conforms
Absorbance at 420nm ≤0.02(at 420nm) Conforms
Warter(KF) ≤2.0% 1.01%
Residue on Ignition ≤0.1% 0.07%
Heavy Metals ≤10ppm <10ppm
Related compounds Compound A 0.55%
Compound B 0.06%
Compound C N.D.
Any other individual impunrity 0.06%
Total impurities (ex.R-isomer) 0.20%
Related Solvents Ethyl acetate 3000ppm
Ethanol N.D.
Toluene 280ppm
Assay(HPLC) 98.0%~102.0% 99.5%
Conclusion Qualified

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